Ornithine decarboxylase- and ras-induced cell transformations: reversal by protein tyrosine kinase inhibitors and role of pp130CAS.
about
Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteinsCMS: an adapter molecule involved in cytoskeletal rearrangementsBCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cellsCell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments.Transformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligandHuman enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiaeTranslocation of ornithine decarboxylase to the surface membrane during cell activation and transformationCAS proteins in normal and pathological cell growth controluPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.Phosphorylated human keratinocyte ornithine decarboxylase is preferentially associated with insoluble cellular proteinsIdentification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signalingCytoskeleton-dependent tyrosine phosphorylation of the p130(Cas) family member HEF1 downstream of the G protein-coupled calcitonin receptor. Calcitonin induces the association of HEF1, paxillin, and focal adhesion kinasep130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogeneRegulation of fibroblast motility by the protein tyrosine phosphatase PTP-PESTDifferential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substratep130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinaseProtein tyrosine phosphatases as negative regulators of mitogenic signalingc-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase.Cas mediates transcriptional activation of the serum response element by Src.PR-39, a syndecan-inducing antimicrobial peptide, binds and affects p130(Cas).A novel putative protein-tyrosine phosphatase contains a BRO1-like domain and suppresses Ha-ras-mediated transformation.The role of the Src homology domains in morphological transformation by v-srcThe role of SRC-CAS interactions in cellular transformation: ectopic expression of the carboxy terminus of CAS inhibits SRC-CAS interaction but has no effect on cellular transformation.N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.Phosphorylation of p130Cas initiates Rac activation and membrane ruffling.Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cellsMechanisms of CAS substrate domain tyrosine phosphorylation by FAK and SrcDistribution patterns of ornithine decarboxylase in cells and tissues: facts, problems, and postulates.A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory NeuroblastomaConstitutive modulation of Raf-1 protein kinase is associated with differential gene expression of several known and unknown genesTamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway.Anti-tumor activity of antizyme which targets the ornithine decarboxylase (ODC) required for cell growth and transformation.Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate.p44/42 mitogen-activated protein kinase is involved in the expression of ornithine decarboxylase in leukaemia L1210 cells.Crk and CrkL adaptor proteins: networks for physiological and pathological signalingThe function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin.Ornithine decarboxylase overexpression in mouse 10T1/2 fibroblasts: cellular transformation and invasion.Phosphorylation of focal adhesion kinase at tyrosine 861 is crucial for Ras transformation of fibroblasts.Cell transformation, invasion, and angiogenesis: a regulatory role for ornithine decarboxylase and polyamines?
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P2860
Ornithine decarboxylase- and ras-induced cell transformations: reversal by protein tyrosine kinase inhibitors and role of pp130CAS.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Ornithine decarboxylase- and r ...... hibitors and role of pp130CAS.
@en
type
label
Ornithine decarboxylase- and r ...... hibitors and role of pp130CAS.
@en
prefLabel
Ornithine decarboxylase- and r ...... hibitors and role of pp130CAS.
@en
P2093
P2860
P356
P1476
Ornithine decarboxylase- and r ...... hibitors and role of pp130CAS.
@en
P2093
Andersson LC
Paasinen-Sohns A
P2860
P304
P356
10.1128/MCB.15.12.6513
P407
P577
1995-12-01T00:00:00Z