Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes.
about
Advances in the characterization of RNA-binding proteinsLong noncoding RNAs in cancer: mechanisms of action and technological advancementsUnveiling the hidden function of long non-coding RNA by identifying its major partner-proteinElucidating the molecular architecture of adaptation via evolve and resequence experimentsSpecificity and nonspecificity in RNA-protein interactionsHigh-throughput characterization of protein-RNA interactionsAffinity regression predicts the recognition code of nucleic acid–binding proteinsSort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relationsA single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting.High-throughput sequencing technologiesBlind tests of RNA nearest-neighbor energy predictionDistributed biotin-streptavidin transcription roadblocks for mapping cotranscriptional RNA folding.Kinetic competition during the transcription cycle results in stochastic RNA processing.New Technologies Provide Quantum Changes in the Scale, Speed, and Success of SELEX Methods and Aptamer Characterization.Protein-responsive ribozyme switches in eukaryotic cells.Long non-coding RNAs in cancer and development: where do we go from here?Enzymatic fabrication of high-density RNA arrays.Probing RNA-protein networks: biochemistry meets genomicsComprehensive analysis of RNA-protein interactions by high-throughput sequencing-RNA affinity profiling.Enzymatic combinatorial nucleoside deletion scanning mutagenesis of functional RNA.Multiple dimensions of epigenetic gene regulation in the malaria parasite Plasmodium falciparum: gene regulation via histone modifications, nucleosome positioning and nuclear architecture in P. falciparumRNA Bind-n-Seq: Measuring the Binding Affinity Landscape of RNA-Binding Proteins.Characterisation of aptamer-target interactions by branched selection and high-throughput sequencing of SELEX pools.Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen.Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains bordersHighly Multiplexed RNA Aptamer Selection using a Microplate-based Microcolumn Device.High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.Rapid RNA-ligand interaction analysis through high-information content conformational and stability landscapes.Quantitative assessment of RNA-protein interactions with high-throughput sequencing-RNA affinity profiling.Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterationsRNA Viruses: RNA Roles in Pathogenesis, Coreplication and Viral LoadRules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution.De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule TherapeuticsSystematic reconstruction of binding and stability landscapes of the fluorogenic aptamer spinachTechnologies to probe functions and mechanisms of long noncoding RNAs.Mechanically Induced Trapping of Molecular Interactions and Its Applications.Revealing protein-lncRNA interactionDeciphering the protein-RNA recognition code: combining large-scale quantitative methods with structural biology.The contribution of the C5 protein subunit of Escherichia coli ribonuclease P to specificity for precursor tRNA is modulated by proximal 5' leader sequences.Mapping specificity landscapes of RNA-protein interactions by high throughput sequencing.
P2860
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P2860
Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Quantitative analysis of RNA-p ...... l and evolutionary landscapes.
@en
type
label
Quantitative analysis of RNA-p ...... l and evolutionary landscapes.
@en
prefLabel
Quantitative analysis of RNA-p ...... l and evolutionary landscapes.
@en
P2093
P2860
P50
P356
P1433
P1476
Quantitative analysis of RNA-p ...... l and evolutionary landscapes.
@en
P2093
Curtis J Layton
Howard Y Chang
Jason D Buenrostro
Michael P Snyder
P2860
P2888
P304
P356
10.1038/NBT.2880
P577
2014-04-13T00:00:00Z