The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.
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TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunitiesTransforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylationTGFβ signalling in contextA novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion.PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling.Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localizationResveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3The Role of SIRT1 in Diabetic Kidney Disease.Flow-dependent Smad2 phosphorylation and TGIF nuclear localization in human aortic endothelial cellsSDF-1/CXCR4 signaling preserves microvascular integrity and renal function in chronic kidney disease.NRF2 deficiency reduces life span of mice administered thoracic irradiation.Aortic Remodelling Is Improved by 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Involving the Smad3 Pathway in Spontaneously Hypertensive Rats.Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticityTranscriptional repression of SIRT1 by protein inhibitor of activated STAT 4 (PIAS4) in hepatic stellate cells contributes to liver fibrosis.To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modificationsAcetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells.The impact of Fli1 deficiency on the pathogenesis of systemic sclerosisPCAF acts as a gastric cancer suppressor through a novel PCAF-p16-CDK4 axisTGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis.Role of Smads in TGFβ signaling.Post-translational regulation of TGF-β receptor and Smad signaling.RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation.Role of Smad signaling in kidney disease.Regulation, Function, and Detection of Protein Acetylation in Bacteria.TGF-β induces miR-30d down-regulation and podocyte injury through Smad2/3 and HDAC3-associated transcriptional repression.Transcriptional Control by the SMADs.High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy.Inhibition of TGF-β signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol.Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification.Temporal Regulation of the Bacillus subtilis Acetylome and Evidence for a Role of MreB Acetylation in Cell Wall Growth.Role of TGFβ signaling in the pathogenesis of Alzheimer's disease.Autoacetylation regulates P/CAF nuclear localization.Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response.Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription.TGF-β1/p53 signaling in renal fibrogenesis.TIMAP repression by TGFβ and HDAC3-associated Smad signaling regulates macrophage M2 phenotypic phagocytosis.Identification and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni.Sirt1 activation ameliorates renal fibrosis by inhibiting the TGF-β/Smad3 pathway.Integration of non-SMAD and SMAD signaling in TGF-beta1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells.Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression.
P2860
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P2860
The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The DNA binding activities of ...... ctivator-mediated acetylation.
@en
type
label
The DNA binding activities of ...... ctivator-mediated acetylation.
@en
prefLabel
The DNA binding activities of ...... ctivator-mediated acetylation.
@en
P2093
P2860
P356
P1476
The DNA binding activities of ...... activator-mediated acetylation
@en
P2093
Carl-Henrik Heldin
Maria Simonsson
Meena Kanduri
P2860
P304
39870-39880
P356
10.1074/JBC.M607868200
P407
P577
2006-10-30T00:00:00Z