Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors.
about
A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entryGenetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: implications for the origin of the novel Middle East respiratUtilization of DC-SIGN for entry of feline coronaviruses into host cellsCrystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptorCrystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptorCrystal Structure of Bovine Coronavirus Spike Protein Lectin DomainProteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.Interaction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2.Structure, Function, and Evolution of Coronavirus Spike Proteins.Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination.Type I feline coronavirus spike glycoprotein fails to recognize aminopeptidase N as a functional receptor on feline cell lines.Protease inhibitors targeting coronavirus and filovirus entryThe receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies.Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response.Receptor recognition mechanisms of coronaviruses: a decade of structural studies.Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like proteaseHost cell proteases: Critical determinants of coronavirus tropism and pathogenesisIdentification of the Receptor-Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1.Evidence for ACE2-utilizing coronaviruses (CoVs) related to severe acute respiratory syndrome CoV in bats.Comparison of SARS and NL63 papain-like protease binding sites and binding site dynamics: inhibitor design implicationsThe novel human coronaviruses NL63 and HKU1.Development of novel entry inhibitors targeting emerging viruses.SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion.Expression of the C-type lectins DC-SIGN or L-SIGN alters host cell susceptibility for the avian coronavirus, infectious bronchitis virusModulation of TNF-alpha-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-alpha production and facilitates viral entryThe spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies.Entry from the cell surface of severe acute respiratory syndrome coronavirus with cleaved S protein as revealed by pseudotype virus bearing cleaved S protein.Link of a ubiquitous human coronavirus to dromedary camels.Evidence for an Ancestral Association of Human Coronavirus 229E with Bats.TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion.The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2.Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1.Mutational analysis of aminopeptidase N, a receptor for several group 1 coronaviruses, identifies key determinants of viral host range.Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders.Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63The first complete genome sequences of clinical isolates of human coronavirus 229E
P2860
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P2860
Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Highly conserved regions withi ...... respective cellular receptors.
@en
type
label
Highly conserved regions withi ...... respective cellular receptors.
@en
prefLabel
Highly conserved regions withi ...... respective cellular receptors.
@en
P2093
P2860
P50
P356
P1433
P1476
Highly conserved regions withi ...... respective cellular receptors.
@en
P2093
Anja Wegele
Chawaree Chaipan
Heike Hofmann
Martina Geier
Paul Bates
Thomas Gramberg
P2860
P304
P356
10.1128/JVI.00560-06
P407
P577
2006-09-01T00:00:00Z