Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase.
about
The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocationSubstrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1Crystal Structures of Human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating Protein (RabGAP) Domains Reveal Critical Elements for GLUT4 TranslocationInsulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilinAS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membraneInsulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesiclesSelf-assembly of Glut4 storage vesicles during differentiation of 3T3-L1 adipocytesDevelopment of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase.Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signalingRegulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association.Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscleTBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis.Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 trafficThe role of multifunctional M1 metallopeptidases in cell cycle progressionGLUT4 exocytosis.Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition.The role of insulin-regulated aminopeptidase in MHC class I antigen presentation.International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.Sustained postexercise increases in AS160 Thr642 and Ser588 phosphorylation in skeletal muscle without sustained increases in kinase phosphorylationRegulatory mode shift of Tbc1d1 is required for acquisition of insulin-responsive GLUT4-trafficking activity.Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle.Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.Ins (endocytosis) and outs (exocytosis) of GLUT4 traffickingInsulin-induced Effects on the Subcellular Localization of AKT1, AKT2 and AS160 in Rat Skeletal Muscle.The sugar is sIRVed: sorting Glut4 and its fellow travelers.A proteolytic pathway that controls glucose uptake in fat and muscle.Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR.Translocation of the insulin-regulated aminopeptidase to the cell surface: detection by radioligand binding.Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.Thrifty Tbc1d1 and Tbc1d4 proteins link signalling and membrane trafficking pathways.Recycling of IRAP from the plasma membrane back to the insulin-responsive compartment requires the Q-SNARE syntaxin 6 but not the GGA clathrin adaptors.The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle.The carboxy-terminal region of the TBC1D4 (AS160) RabGAP mediates protein homodimerization.
P2860
Q24293287-53DAF57C-4F92-43E6-814D-9CFA88CB717CQ24683047-C4336B6F-CAD0-4624-929E-6C6BF5152D2DQ27667369-E6F2D82D-AADB-4E50-A9DF-FBA2D9E8FEB6Q28297062-A167D58D-63B0-4145-A922-F8A6C9923193Q28580015-53C82D82-DF33-4B50-9837-A3C03D80022DQ30434989-81907E85-AE28-42EF-9063-D83190CC2D81Q30438095-E544B1D1-DA68-453A-A00E-D50995F0B29AQ33393907-2283BC2C-80A2-4909-A031-7CADC99400A4Q33581145-AFEA1E60-C629-4535-B96F-99687167ACB3Q33642606-19A5EC6B-0BD6-49AC-A096-03ECE6B3B63EQ33655561-5E50CF1A-82B7-4B42-9F72-B84C18CC8E1DQ33869742-F89F71A0-EC1D-43E7-AC39-7C0D70BEBB7CQ34385634-396D8B4A-8D75-4EB3-8B03-091C59FCA27CQ34629081-22CBD63C-8AE5-4BD0-8082-AE74C38C016CQ34778453-FBE0E662-D389-4628-8D0C-F2C8C99D83ECQ34968850-A8F057C6-433E-46D5-B90F-AB4ACE782CEAQ35672106-D9AE4EC1-BEF0-4F6C-BC90-88CD33FD008DQ35766154-5A38A294-0DAD-4BCE-A18E-BFF026153C7BQ35928365-4BF33B8D-2E89-4A2B-B719-C39EC43CD8B0Q36241932-6167CA18-C750-42F2-ACCF-7EF1FAB50E5FQ36435173-353BE22D-7887-4093-8A9C-F41017BA27ECQ36530922-9294F2F5-A811-4D1B-8321-C26E551D49B2Q36680563-BD7A704D-47F1-4D0A-BD0A-3A04CE833566Q36767833-83C75E8D-5236-4AAE-BB9C-284B0B64036CQ36825642-8D0F5F1C-9B6B-4613-AA7A-E2C2A9436C52Q36888387-DDB50BF5-DAB5-4580-8B99-741AAACA489DQ37501407-A25552B0-712A-47F2-B612-339965B739BBQ37838504-4A5F91F3-F784-4D34-B07F-2F74BA8E1B88Q38151511-A704CF7D-CC40-44E5-9EB2-FA7E02678B8DQ39252731-6D2238B0-660A-40C4-8362-0D4ED79BE5B6Q39572817-3B62C4AE-B98F-42E3-A475-BF3A08CBAD3AQ39646969-DB2AB1EB-4F45-4DF0-BB82-6DCBC98F1F23Q41910564-37078C12-9DEF-4805-9E89-8DE3F58D02C8Q42152599-589D3016-531E-443B-A7A5-6CBF88302739Q46879323-C88D82D4-9099-46B0-B294-444EF933B0D1Q50978850-6E426D08-CA80-4EC5-9E20-AA48105E834C
P2860
Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Interaction of the Akt substra ...... ulin-regulated aminopeptidase.
@en
type
label
Interaction of the Akt substra ...... ulin-regulated aminopeptidase.
@en
prefLabel
Interaction of the Akt substra ...... ulin-regulated aminopeptidase.
@en
P2093
P356
P1476
Interaction of the Akt substra ...... ulin-regulated aminopeptidase.
@en
P2093
Anthony L Albiston
Grantley R Peck
Ruani N Fernando
S Lance Macaulay
Siew Yeen Chai
P304
P356
10.1210/ME.2005-0476
P50
P577
2006-06-08T00:00:00Z