Impaired germinal center reaction in mice with short telomeres.
about
Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.The telomere syndromesMutations in the SBDS gene in acquired aplastic anemiaTelomerase activity and telomere length in male germ cellsTelomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivoVaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variantsTelomere attrition due to infection.Composition and function of haemolymphatic tissues in the European common shrew.Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions.Sex-related differences in length and erosion dynamics of human telomeres favor females.Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.Cell senescence and cancer.The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.Microenvironmental regulation of telomerase isoforms in human embryonic stem cellsAlternative lengthening of telomeres in mammalian cells.Telomerase activity and clinical progression in chronic lymphoproliferative disorders of B-cell lineage.Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.Telomerase and cancer: time to move from a promising target to a clinical reality.Telomeres, aging and cancer: in search of a happy ending.Many ways to telomere dysfunction: in vivo studies using mouse models.Telomeres in T and B cells.Telomere maintenance and cancer -- look, no telomerase.Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptaseDNA fusion gene vaccines against cancer: from the laboratory to the clinic.In vivo regulation of telomerase activity and telomere length.Telomerase activation and rejuvenation of telomere length in stimulated T cells derived from serially transplanted hematopoietic stem cellsTelomere length dynamics in normal hematopoiesis and in disease states characterized by increased stem cell turnover.Alternative lengthening of telomeres in normal mammalian somatic cells.Telomere regulation and function during meiosis.Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells.Telomere dysfunction and tumour suppression: the senescence connectionA 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAsExtracting extra-telomeric phenotypes from telomerase mouse models.Telomerase at the intersection of cancer and aging.Epigenetic regulation of telomere chromatin integrity in pluripotent embryonic stem cells.Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species.Stem cell function and maintenance - ends that matter: role of telomeres and telomerase.How T follicular helper cells and the germinal centre response change with age.
P2860
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P2860
Impaired germinal center reaction in mice with short telomeres.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Impaired germinal center reaction in mice with short telomeres.
@en
type
label
Impaired germinal center reaction in mice with short telomeres.
@en
prefLabel
Impaired germinal center reaction in mice with short telomeres.
@en
P2860
P356
P1433
P1476
Impaired germinal center reaction in mice with short telomeres
@en
P2093
C Martínez-A
P2860
P304
P356
10.1093/EMBOJ/19.3.472
P407
P577
2000-02-01T00:00:00Z