Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation. - Wikidata - wikimedia - TriplyDB

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.

http://www.wikidata.org/entity/Q34446515

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The telomere syndromes Role of Telomerase in the Cardiovascular System Oxidative stress-induced telomeric erosion as a mechanism underlying airborne particulate matter-related cardiovascular disease Axis of ageing: telomeres, p53 and mitochondria Origin of cardiomyocytes in the adult heart Telomeres and Telomerase in Cardiovascular Diseases Linking functional decline of telomeres, mitochondria and stem cells during ageing An intricate dance: Life experience, multisystem resiliency, and rate of telomere decline throughout the lifespan On cross-sectional associations of leukocyte telomere length with cardiac systolic, diastolic and vascular function: the Asklepios study Age-Related Left Ventricular Changes and Their Association with Leukocyte Telomere Length in Healthy People Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA).A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.Role of stem cells in cardiovascular biology.p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo.Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure Aging, telomeres and heart failure.Aging and HIV/AIDS: pathogenetic role of therapeutic side effects Telomere dysfunction induces metabolic and mitochondrial compromise.Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86 Overexpression of ankyrin repeat domain 1 enhances cardiomyocyte apoptosis by promoting p53 activation and mitochondrial dysfunction in rodents.Healthy aging and disease: role for telomere biology?Functional role of Calstabin2 in age-related cardiac alterations.Increased p53 activity does not accelerate telomere-driven ageing.Telomere attrition and Chk2 activation in human heart failure Mechanical unloading promotes myocardial energy recovery in human heart failure.Cardiomyogenesis in the developing heart is regulated by c-kit-positive cardiac stem cells.Telomeres, telomerase, and apoptosis.Death begets failure in the heart.Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres.Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.Increased mitotic rate coincident with transient telomere lengthening resulting from pim-1 overexpression in cardiac progenitor cells.Telomerase expression in the mammalian heart p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice Empowering Adult Stem Cells for Myocardial Regeneration V2.0: Success in Small Steps.Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase.Assessing cell and organ senescence biomarkers Telomere dynamics during aging in polygenic left ventricular hypertrophy.Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction.Telomeres and mitochondria in the aging heart.

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P2860

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.

http://www.wikidata.org/entity/Q34446515

description

2003 nî lūn-bûn

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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2003年の論文

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Ablation of telomerase and tel ...... ociated with p53 upregulation.

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Annarosa Leri

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Antonella Zacheo

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Bernardo Nadal-Ginard

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Federica Limana

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Jan Kajstura

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Sonia Franco

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Stefano Chimenti

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P2860

Extension of life-span by introduction of telomerase into normal human cells

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.

Bone marrow cells regenerate infarcted myocardium

Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice

Telomeres shorten during ageing of human fibroblasts

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

Protection of mammalian telomeres

Essential role of mouse telomerase in highly proliferative organs

Mobilized bone marrow cells repair the infarcted heart, improving function and survival.

Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.

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