The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis.
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In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissuesPTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestineThe alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-cateninPTK6 regulates IGF-1-induced anchorage-independent survival.Brk/PTK6 signaling in normal and cancer cell models.Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRKEvolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapyBreast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells.PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors.RAKing in AKT: a tumor suppressor function for the intracellular tyrosine kinase FRK.Conditionally immortalized colonic epithelial cell line from a Ptk6 null mouse that polarizes and differentiates in vitro.Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine.Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells.Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim.PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas.Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients.Protein tyrosine kinase 6 is associated with nasopharyngeal carcinoma poor prognosis and metastasis.Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage.Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis.Protein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models.Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer.Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer.Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma.
P2860
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P2860
The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年學術文章
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2005年學術文章
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2005年學術文章
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name
The intracellular tyrosine kin ...... ells to inducers of apoptosis.
@en
type
label
The intracellular tyrosine kin ...... ells to inducers of apoptosis.
@en
prefLabel
The intracellular tyrosine kin ...... ells to inducers of apoptosis.
@en
P2093
P356
P1433
P1476
The intracellular tyrosine kin ...... ells to inducers of apoptosis.
@en
P2093
Andrea Haegebarth
Angela L Tyner
Rafael Nunez
P304
P356
10.4161/CC.4.9.1965
P577
2005-09-23T00:00:00Z