Opioid receptor homo- and heterodimerization in living cells by quantitative bioluminescence resonance energy transfer.
about
Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerizationClinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeysThe δ opioid receptor agonist SNC80 selectively activates heteromeric μ-δ opioid receptorsStandard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonistsNovel GPCR paradigms at the μ-opioid receptorOpioid receptor heteromers in analgesiaOligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors.Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimersA bivalent ligand (KMN-21) antagonist for mu/kappa heterodimeric opioid receptorsDirect interaction of GABAB receptors with M2 muscarinic receptors enhances muscarinic signaling.The physical association of the P2Y12 receptor with PAR4 regulates arrestin-mediated Akt activation.Search for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor.Emergence of functional spinal delta opioid receptors after chronic ethanol exposureContribution of mu and delta opioid receptors to the pharmacological profile of kappa opioid receptor subtypes.Diversifying the repertoire of G protein-coupled receptors through oligomerization.Opioid-receptor-heteromer-specific trafficking and pharmacology.Putative kappa opioid heteromers as targets for developing analgesics free of adverse effects.Probing novel GPCR interactions using a combination of FRET and TIRFHow to design an opioid drug that causes reduced tolerance and dependence.Making structural sense of dimerization interfaces of delta opioid receptor homodimers.N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromersHeterologous regulation of Mu-opioid (MOP) receptor mobility in the membrane of SH-SY5Y cells.Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10.Differential response to morphine of the oligomeric state of μ-opioid in the presence of δ-opioid receptorsHeteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities.Recent advances on the δ opioid receptor: from trafficking to function.Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys.Allosteric interactions between δ and κ opioid receptors in peripheral sensory neuronsmRNA transcript diversity creates new opportunities for pharmacological intervention.Opiate antagonist prevents μ- and δ-opiate receptor dimerization to facilitate ability of agonist to control ethanol-altered natural killer cell functions and mammary tumor growth.Mu opioid receptor regulation and opiate responsiveness.Application of bioluminescence resonance energy transfer (BRET) for biomolecular interaction studies.Acute delta- and kappa-opioid agonist pretreatment potentiates opioid antagonist-induced suppression of water consumptionMolecular mechanisms of opioid receptor-dependent signaling and behavior.Molecular Pharmacology of δ-Opioid Receptors.Ignavine: a novel allosteric modulator of the μ opioid receptorFunctional characterization of human variants of the mu-opioid receptor genePurification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.G Protein-Coupled Receptor Heteromers.
P2860
Q24300182-62208E61-1110-4A52-8958-41B9A14ADD37Q24597777-67F4EF13-AA98-40D8-AF92-FF44316144CAQ24630886-7813DA14-2B30-473B-8343-F01FA3B02466Q24631212-2324F94E-6AA6-4451-A1B8-6B8386A45F53Q26864286-C3FAB3D7-B451-4062-81F7-13DC9F39D793Q27004306-675E4DC1-7BFD-47EE-9F21-685F4AE2F03BQ27929513-9501B29C-0F8F-4400-8047-52D6BC8D975BQ28584024-9BC270A7-B466-4F61-93CA-0939035901FBQ28822182-0AB3B9F2-A004-458F-BA48-F3B6D4789689Q33637415-948865B1-9430-4DF2-86CE-6F031097969FQ33742756-16B07763-D410-44C5-B261-2CA23F9C9D19Q33807778-D3209749-8999-4F44-BA69-1AFFCA8F4D02Q33863121-8C1E4849-8738-40AD-BDB0-F299FFF787A8Q33863139-6EF51573-23D5-4CFE-90D6-85A4DBD874ABQ33863332-E63D9528-3773-44F9-A1C1-861D6EBF309FQ33978499-BF26EEA8-D244-4BE6-A165-EFEF233DB64FQ34061067-0E4957F4-F3CC-4367-A668-64F7BE648C58Q34084413-27C74E96-1B40-4748-8A23-15139D3A352FQ34144947-0759D1D9-4CD0-4B5B-AA1A-C8C6EA89EAE1Q34160481-1A6C5EB9-F16C-43C5-B409-E5CD4E07F4AFQ34169318-644EC6A2-533F-48B5-A8F2-425AC91F5593Q34317508-7F3238B8-7119-4003-B7FA-E2D6725E282EQ34424009-2E2C1D88-40B9-4394-A474-A7F98E401157Q34767171-FBC532FA-F9E2-4441-8A23-7976259CD131Q34939624-8DC024C6-E198-4907-8F85-3EDCF6AEFB5CQ34939664-31999D3A-6780-45E1-8104-DF3367F3B82DQ35213193-5E2496A2-5819-4548-AB9D-B9524A9DA3A4Q35545574-34B3796B-46DE-4B56-9983-8DD8D2693F2FQ35688476-05B3207C-D18D-4E05-A678-4823265375CDQ35913120-F4E027C5-373C-40D3-8E6C-A87C3464B78BQ35956747-78EA69C0-2BEF-40E7-9328-A4854C92A80AQ36341679-BF5A1688-207C-4BEB-A5EC-68E357BB9ADBQ36498179-0E3C993B-CF33-404E-B841-EBE7D0867F69Q36825466-939625AB-F5C1-4465-8160-D3221BFD57E0Q36974487-E1912292-CB25-4A67-8CFA-6A31B63D7117Q37062556-276A8463-AC47-40A6-919E-73485EB34736Q37181467-9491C36D-DB90-4D29-BF1E-EC8C56470D1CQ37249905-D6F5F6C0-CC35-4F43-9CA7-BBD1A718ACB6Q37446783-13957B9C-27F9-4620-8263-67599DDDB3B2Q37489251-F914BCDE-6D34-4B89-BCED-E360DAC1A5B1
P2860
Opioid receptor homo- and heterodimerization in living cells by quantitative bioluminescence resonance energy transfer.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Opioid receptor homo- and hete ...... nce resonance energy transfer.
@en
type
label
Opioid receptor homo- and hete ...... nce resonance energy transfer.
@en
prefLabel
Opioid receptor homo- and hete ...... nce resonance energy transfer.
@en
P2093
P356
P1476
Opioid receptor homo- and hete ...... nce resonance energy transfer.
@en
P2093
Danxin Wang
Wolfgang Sadée
Xiaochun Sun
P304
P356
10.1124/MOL.104.010272
P50
P577
2005-03-18T00:00:00Z