ATM-related genes: what do they tell us about functions of the human gene?
about
Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complexA role for ATR in the DNA damage-induced phosphorylation of p53Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaksInvolvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindlePhosphorylation of DNA topoisomerase I by the c-Abl tyrosine kinase confers camptothecin sensitivityDNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during developmentPhosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damageSaccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathwayscDNA cloning and gene mapping of a candidate human cell cycle checkpoint proteinS-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombeImmunoglobulin class switch recombination is impaired in Atm-deficient miceOverexpression of a truncated human topoisomerase III partially corrects multiple aspects of the ataxia-telangiectasia phenotypePathogenesis of ataxia-telangiectasia: the next generation of ATM functionsNORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae.Characterization of DNA damage-stimulated self-interaction of Saccharomyces cerevisiae checkpoint protein Rad17p.Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damageSubstrate specificities and identification of putative substrates of ATM kinase family membersRecruitment of ATM protein to double strand DNA irradiated with ionizing radiationCarboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitroThe mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminusAntifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionWortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionAtaxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expressionCancer risk and the ATM gene: a continuing debate.Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesisThe plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner.Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity.Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice.Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.Cell-surface expression of transrearranged Vgamma-cbeta T-cell receptor chains in healthy donors and in ataxia telangiectasia patients.Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoiningMultifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenanceAtaxia telangiectasia gene mutations in leukaemia and lymphoma.Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinaseIdentification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance.ATM, a central controller of cellular responses to DNA damage.Damage control: the pleiotropy of DNA repair genes in Drosophila melanogasterThe Aspergillus nidulans uvsB gene encodes an ATM-related kinase required for multiple facets of the DNA damage response.Identification and analysis of a hyperactive mutant form of Drosophila P-element transposase.
P2860
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P2860
ATM-related genes: what do they tell us about functions of the human gene?
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
ATM-related genes: what do they tell us about functions of the human gene?
@en
type
label
ATM-related genes: what do they tell us about functions of the human gene?
@en
prefLabel
ATM-related genes: what do they tell us about functions of the human gene?
@en
P1433
P1476
ATM-related genes: what do they tell us about functions of the human gene?
@en
P2093
P304
P356
10.1016/0092-8674(95)90463-8
P407
P577
1995-09-01T00:00:00Z