Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity.
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityHuman BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCDNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchangeSumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodiesE3 ubiquitin ligase COP1 regulates the stability and functions of MTA1Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexesHuman MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresATM phosphorylates histone H2AX in response to DNA double-strand breaksNuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells53BP1 is associated with replication protein A and is required for RPA2 hyperphosphorylation following DNA damageMORC2 signaling integrates phosphorylation-dependent, ATPase-coupled chromatin remodeling during the DNA damage responseATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage.DNA replication but not nucleotide excision repair is required for UVC-induced replication protein A phosphorylation in mammalian cellsUV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.Regulation of dna replication after heat shock by replication protein a-nucleolin interactions.Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase.Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.Cancer risk and the ATM gene: a continuing debate.Replication protein A is sequentially phosphorylated during meiosis.Replication protein A (RPA) phosphorylation prevents RPA association with replication centers.DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells.Neuronal death is an active, caspase-dependent process after moderate but not severe DNA damage.Wortmannin potentiates integrase-mediated killing of lymphocytes and reduces the efficiency of stable transduction by retroviruses.Phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21.Modulation of replication protein A function by its hyperphosphorylation-induced conformational change involving DNA binding domain B.Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responsesRegulation of replication protein A functions in DNA mismatch repair by phosphorylation.ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiationNBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse.Human DNA repair systems: an overview.DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine.An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis.Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.Molecular interaction map of the mammalian cell cycle control and DNA repair systems.Ionizing radiation-dependent gamma-H2AX focus formation requires ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3-related.ATM: a mediator of multiple responses to genotoxic stress.The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.Atm inactivation results in aberrant telomere clustering during meiotic prophase.Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment
P2860
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P2860
Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity.
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Characterization of ATM expres ...... ndent protein kinase activity.
@ast
Characterization of ATM expres ...... ndent protein kinase activity.
@en
type
label
Characterization of ATM expres ...... ndent protein kinase activity.
@ast
Characterization of ATM expres ...... ndent protein kinase activity.
@en
prefLabel
Characterization of ATM expres ...... ndent protein kinase activity.
@ast
Characterization of ATM expres ...... ndent protein kinase activity.
@en
P2093
P2860
P356
P1476
Characterization of ATM expres ...... ndent protein kinase activity.
@en
P2093
P2860
P304
P356
10.1091/MBC.9.9.2361
P577
1998-09-01T00:00:00Z