Self-inactivating retroviral vectors with improved RNA processing. - Wikidata - wikimedia - TriplyDB

Self-inactivating retroviral vectors with improved RNA processing.

Self-inactivating retroviral vectors with improved RNA processing.

http://www.wikidata.org/entity/Q40515056

about

Impact of age at administration, lysosomal storage, and transgene regulatory elements on AAV2/8-mediated rat liver transduction Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral Vectors An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors A self-inactivating gamma-retroviral vector reduces manifestations of mucopolysaccharidosis I in mice Dynamic clonal analysis of murine hematopoietic stem and progenitor cells marked by 5 fluorescent proteins using confocal and multiphoton microscopy.The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.Self-inactivating retroviral vector-mediated gene transfer induces oncogene activation and immortalization of primary murine bone marrow cells.Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.Update on gene therapy for immunodeficiencies.Scale-up and manufacturing of clinical-grade self-inactivating γ-retroviral vectors by transient transfection BCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation.Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors Evaluation of residual promoter activity in γ-retroviral self-inactivating (SIN) vectors.Versatility of gene therapy vectors through viruses.Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells.Stable gammaretroviral vector expression during embryonic stem cell-derived in vitro hematopoietic development.Reducing the genotoxic potential of retroviral vectors.Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology.Combinatorial incorporation of enhancer-blocking components of the chicken beta-globin 5'HS4 and human T-cell receptor alpha/delta BEAD-1 insulators in self-inactivating retroviral vectors reduces their genotoxic potential.Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells.Lentiviral vectors with amplified beta cell-specific gene expression.Gene therapy for heart failure: where do we stand?Alpharetroviral vectors: from a cancer-causing agent to a useful tool for human gene therapy.Retroviral Transduction of T Cells and T Cell Precursors A 38 nt region and its flanking sequences within gag of Friend murine leukemia virus are crucial for splicing at the correct 5' and 3' splice sites.Evolving Gene Therapy in Primary Immunodeficiency.CCAAT/enhancer-binding protein beta inhibits proliferation in monocytic cells by affecting the retinoblastoma protein/E2F/cyclin E pathway but is not directly required for macrophage morphology.A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors Murine leukemia virus regulates alternative splicing through sequences upstream of the 5' splice site.Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors.Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression.Elements of lentiviral vector design toward gene therapy for treating mucopolysaccharidosis I.New way of regulating alternative splicing in retroviruses: the promoter makes a difference.Critical variables affecting clinical-grade production of the self-inactivating gamma-retroviral vector for the treatment of X-linked severe combined immunodeficiency.Towards hematopoietic stem cell-mediated protection against infection with human immunodeficiency virus.Gamma-glutamylcysteine synthetase-based selection strategy for gene therapy of chronic granulomatous disease and graft-vs.-host disease.Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene.Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy.

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Self-inactivating retroviral vectors with improved RNA processing.

http://www.wikidata.org/entity/Q40515056

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Self-inactivating retroviral vectors with improved RNA processing.

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type

label

Self-inactivating retroviral vectors with improved RNA processing.

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prefLabel

Self-inactivating retroviral vectors with improved RNA processing.

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Self-inactivating retroviral vectors with improved RNA processing

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Baum C

http://www.w3.org/2001/XMLSchema#string

Bohne J

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Brandenburg G

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Kraunus J

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Meyer J

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Modlich U

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Schambach A

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Schaumann DH

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von Laer D

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P2860

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation

Stimulatory effect of splicing factors on transcriptional elongation

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

Plat-E: an efficient and stable system for transient packaging of retroviruses

Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos.

Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells.

Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro

Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells

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1568-1578

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10.1038/SJ.GT.3302309

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21

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11

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15372067

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