Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.
about
Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expressionPolycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic ImplicationsThe enhancer of trithorax and polycomb corto interacts with cyclin G in Drosophila.Comprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell linesPolycomb group proteins: multi-faceted regulators of somatic stem cells and cancer.Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells.Polycomb group-dependent Cyclin A repression in DrosophilaQuantitative analysis of EZH2 expression and its correlations with lung cancer patients' clinical pathological characteristics.Epigenetic regulation of cardiac myocyte differentiation.The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila developmentConnections between epigenetic gene silencing and human disease.Suppression of centrosome duplication and amplification by deacetylases.HDAC Inhibition for the Treatment of Epithelioid Sarcoma: Novel Cross Talk Between Epigenetic Components.Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma.Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation.Polycomb and the emerging epigenetics of pancreatic cancer.EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasisDownregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1Role of EZH2 histone methyltrasferase in melanoma progression and metastasisPolycomb group protein enhancer of zeste 2 is an oncogene that promotes the neoplastic transformation of a benign prostatic epithelial cell lineOn the role of retinoblastoma family proteins in the establishment and maintenance of the epigenetic landscape.The novel EZH2 inhibitor, GSK126, suppresses cell migration and angiogenesis via down-regulating VEGF-A.Inorganic arsenic exposure induces E2F-dependent G0/G1 arrest via an increase in retinoblastoma family protein p130 in B-cell lymphoma A20 cells.Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer.S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition.Targeting Enhancer of Zeste Homolog 2 as a promising strategy for cancer treatmentExpression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer.Drosophila RB proteins repress differentiation-specific genes via two different mechanisms.Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells.Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer.High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapyPost-translational Modification-Based Regulation of HIV Replication
P2860
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P2860
Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Ezh2 reduces the ability of HD ...... tional repression of cyclin A.
@en
type
label
Ezh2 reduces the ability of HD ...... tional repression of cyclin A.
@en
prefLabel
Ezh2 reduces the ability of HD ...... tional repression of cyclin A.
@en
P2093
P2860
P356
P1433
P1476
Ezh2 reduces the ability of HD ...... tional repression of cyclin A.
@en
P2093
Giuseppina D'Andrilli
Luigi Bagella
Tiziana Tonini
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207608
P407
P577
2004-06-01T00:00:00Z
P5875
P6179
1001874663