RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation. - Wikidata - wikimedia - TriplyDB

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation.

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation.

http://www.wikidata.org/entity/Q40598895

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Deficiency of the NHE1 gene prevents hypoxia-induced pulmonary hypertension and vascular remodeling Role of G-proteins in the differentiation of epiphyseal chondrocytes The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation.Identification and validation of quantitative trait loci (QTL) for canine hip dysplasia (CHD) in German Shepherd Dogs Formin 1 and filamin B physically interact to coordinate chondrocyte proliferation and differentiation in the growth plate Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy.Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation.Inhibition of Rac and ROCK signalling influence osteoblast adhesion, differentiation and mineralization on titanium topographies.Engineering a fibrocartilage spectrum through modulation of aggregate redifferentiation.Cell-mediated degradation regulates human mesenchymal stem cell chondrogenesis and hypertrophy in MMP-sensitive hyaluronic acid hydrogels.Strategies to minimize hypertrophy in cartilage engineering and regeneration.miR-340 suppresses glioblastoma multiforme Simvastatin enhances Rho/actin/cell rigidity pathway contributing to mesenchymal stem cells' osteogenic differentiation Src kinase inhibition promotes the chondrocyte phenotype.Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy.Wnt and Rho GTPase signaling in osteoarthritis development and intervention: implications for diagnosis and therapy.Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes.MRTF-A and STAT3 promote MDA-MB-231 cell migration via hypermethylating BRSM1.Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53-dependent apoptosis without enhancing proliferation.Chondrocyte culture in three dimensional alginate sulfate hydrogels promotes proliferation while maintaining expression of chondrogenic markers.Rac1 signaling stimulates N-cadherin expression, mesenchymal condensation, and chondrogenesis.The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms.Mechanical microenvironments and protein expression associated with formation of different skeletal tissues during bone healing.Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-alpha signalling in endochondral bone growth.Effect of nitrogen-rich cell culture surfaces on type X collagen expression by bovine growth plate chondrocytes.Alendronate inhibits VEGF expression in growth plate chondrocytes by acting on the mevalonate pathway.The vacuolar H+ ATPase V0 subunit d2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation.Peroxisome proliferator-activated receptor δ promotes the progression of posttraumatic osteoarthritis in a mouse model.Rho/ROCK and MEK/ERK activation by transforming growth factor-alpha induces articular cartilage degradation.Human stanniocalcin-1 or -2 expressed in mice reduces bone size and severely inhibits cranial intramembranous bone growth.Lidocaine induces ROCK-dependent membrane blebbing and subsequent cell death in rabbit articular chondrocytes.Role of interleukin-10 in endochondral bone formation in mice: anabolic effect via the bone morphogenetic protein/Smad pathway.Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.Regulation of SOX9 mRNA in human articular chondrocytes involving p38 MAPK activation and mRNA stabilization.RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner.Rho-kinase inhibitor Y-27632 increases cellular proliferation and migration in human foreskin fibroblast cells.

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P2860

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation.

http://www.wikidata.org/entity/Q40598895

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation.

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type

label

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation.

@en

prefLabel

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation.

@en

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Journal of Biological Chemistry

P1476

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation

@en

P2093

Anita Woods

http://www.w3.org/2001/XMLSchema#string

Guoyan Wang

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Lee-Anne Stanton

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Luca Pagnotta

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Shalev Sabari

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P2860

Rocks: multifunctional kinases in cell behaviour

Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of Rho guanine nucleotide exchange factors

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

Regulation and functions of Rho-associated kinase

Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome

Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1

The role of RhoA in tissue polarity and Frizzled signalling

In situ hybridization studies on the expression of type X collagen in fetal human cartilage

A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia

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13205-13214

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10.1074/JBC.M311427200

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13

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279

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14726536

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