Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells. - Wikidata - wikimedia - TriplyDB

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

http://www.wikidata.org/entity/Q40598947

about

The notch ligand JAGGED1 as a target for anti-tumor therapy Skeletrophin, a novel ubiquitin ligase to the intracellular region of Jagged-2, is aberrantly expressed in multiple myeloma Multiple myeloma cancer stem cells Notch Signaling in Neuroendocrine Tumors Notch signaling: its roles and therapeutic potential in hematological malignancies Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?Notch signaling deregulation in multiple myeloma: A rational molecular target The tumor microenvironment shapes hallmarks of mature B-cell malignancies.Evidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma.NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomas Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays.Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.Notch inhibitors for cancer treatment.miRSystem: an integrated system for characterizing enriched functions and pathways of microRNA targets.Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.Notch signaling in serous ovarian cancer.Combined inhibition of Notch signaling and Bcl-2/Bcl-xL results in synergistic antimyeloma effect.Targeting the notch ligand JAGGED1 in both tumor cells and stroma in ovarian cancer.MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma.Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.Bone marrow microenvironment and the identification of new targets for myeloma therapy.Novel therapeutic strategies targeting growth factor signalling cascades in multiple myeloma.Notch signaling in T-cell acute lymphoblastic leukemia.Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45 Overexpression of the Notch3 receptor and its ligand Jagged1 in human clinically non-functioning pituitary adenomas Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Structure and function of the solid tumor niche.Reelin promotes the adhesion and drug resistance of multiple myeloma cells via integrin β1 signaling and STAT3.Anti-myeloma effect of pharmacological inhibition of Notch/gamma-secretase with RO4929097 is mediated by modulation of tumor microenvironment.Multiple myeloma cancer stem cells Gamma secretase inhibitors of Notch signaling Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition Notch1 mediates growth suppression of papillary and follicular thyroid cancer cells by histone deacetylase inhibitors.Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.Mechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies.Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche.Tumor-infiltrating myeloid cells activate Dll4/Notch/TGF-β signaling to drive malignant progression Targeting the Notch signaling pathway in autoimmune diseases.

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P2860

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

http://www.wikidata.org/entity/Q40598947

description

2004 nî lūn-bûn

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2004年の論文

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2004年论文

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2004年论文

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2004年论文

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name

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

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Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

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Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

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Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

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