Epidermal growth factor receptor: association of extracellular domain negatively regulates intracellular kinase activation in the absence of ligand.
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Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segmentConformational coupling across the plasma membrane in activation of the EGF receptorSpatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1Emerging therapies in gastrointestinal cancers.Mutation of Cys105 inhibits dimerization of p12CDK2-AP1 and its growth suppressor effect.Regulation of the catalytic activity of the EGF receptor.Therapeutic potential of EGFR-related protein, a universal EGFR family antagonist.Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivoExploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach.Transmembrane helix-helix interactions involved in ErbB receptor signaling.Receptor tyrosine kinase signaling--a proteomic perspective.SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor.Potential for modulation of the fas apoptotic pathway by epidermal growth factor in sarcomas.An EGFR gene of the Pacific oyster Crassostrea gigas functions in wound healing and promotes cell proliferation.Ligand binding induces a conformational change in epidermal growth factor receptor dimers.Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation.Ligand-induced EGF receptor oligomerization is kinase-dependent and enhances internalization.Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis.The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.Potential for functional redundancy in EGF and TGFalpha signaling in desmoid cells: a cDNA microarray analysis.Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment.Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor.Phosphorylation of epidermal growth factor receptor and chromosome 7 polysomy in gastric adenocarcinoma.
P2860
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P2860
Epidermal growth factor receptor: association of extracellular domain negatively regulates intracellular kinase activation in the absence of ligand.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Epidermal growth factor recept ...... tion in the absence of ligand.
@en
type
label
Epidermal growth factor recept ...... tion in the absence of ligand.
@en
prefLabel
Epidermal growth factor recept ...... tion in the absence of ligand.
@en
P2093
P2860
P1476
Epidermal growth factor recept ...... tion in the absence of ligand.
@en
P2093
Antony W Burgess
Francesca Walker
Hong-Jian Zhu
Josephine Iaria
Suzanne Orchard
P2860
P356
10.1080/0897719031000096424
P577
2003-03-01T00:00:00Z