Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties.
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A form of the metabolic syndrome associated with mutations in DYRK1BMirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblastsThe zebrafish dyrk1b gene is important for endoderm formationThe adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species.The kinase Mirk is a potential therapeutic target in osteosarcoma.Development of a sensitive non-radioactive protein kinase assay and its application for detecting DYRK activity in Xenopus laevis oocytesThe normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen speciesMirk kinase inhibition targets ovarian cancer ascites.Mirk/dyrk1B kinase is upregulated following inhibition of mTOR.Depleting Mirk Kinase Increases Cisplatin Toxicity in Ovarian Cancer Cells.The role of mirk kinase in sarcomasInactivation of mirk/dyrk1b kinase targets quiescent pancreatic cancer cells.New targets to treat obesity and the metabolic syndrome.Ovarian cancer cells, not normal cells, are damaged by Mirk/Dyrk1B kinase inhibition.The Kinase Mirk/dyrk1B: A Possible Therapeutic Target in Pancreatic CancerTransient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/RB2.Mirk/dyrk1B Kinase in Ovarian Cancer.DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain.Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.Comprehensive DNA Methylation and Gene Expression Profiling in Differentiating Human Adipocytes.The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.Targeting DYRK1B suppresses the proliferation and migration of liposarcoma cells.
P2860
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P2860
Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Alternative splicing variants ...... ion and functional properties.
@en
type
label
Alternative splicing variants ...... ion and functional properties.
@en
prefLabel
Alternative splicing variants ...... ion and functional properties.
@en
P2093
P2860
P356
P1433
P1476
Alternative splicing variants ...... ion and functional properties.
@en
P2093
Andreas Barthel
Barbara Maenz
Hanna Czajkowska
Katrin De Graaf
Susanne Leder
P2860
P304
P356
10.1042/BJ20030182
P407
P577
2003-06-01T00:00:00Z