Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. - Wikidata - wikimedia - TriplyDB

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.

http://www.wikidata.org/entity/Q40735691

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Hereditary chronic pancreatitis Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis Biochemical models of hereditary pancreatitis The role of Transient Receptor Potential Vanilloid 1 (TRPV1) channels in pancreatitis Cathepsin B cleavage of the trypsinogen activation peptide.PKD signaling and pancreatitis Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate Central role of neutrophil in the pathogenesis of severe acute pancreatitis Review of experimental animal models of biliary acute pancreatitis and recent advances in basic research Acute pancreatitis in children and adolescents Pathophysiology of acute pancreatitis: potential application from experimental models and human medicine to dogs Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein Cathepsin B Expression and the Correlation with Clinical Aspects of Oral Squamous Cell Carcinoma Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications Review of experimental animal models of acute pancreatitis p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection Cathepsin B localizes to plasma membrane caveolae of differentiating myoblasts and is secreted in an active form at physiological pH Protection from pancreatitis by the zymogen granule membrane protein integral membrane-associated protein-1 Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors Profiling trait anxiety: transcriptome analysis reveals cathepsin B (Ctsb) as a novel candidate gene for emotionality in mice The NALP3 inflammasome is involved in the innate immune response to amyloid-beta Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.VASP-E: specificity annotation with a volumetric analysis of electrostatic isopotentials.Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells.RAB26 coordinates lysosome traffic and mitochondrial localization.Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis.IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse.Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.Zymogen activation in a reconstituted pancreatic acinar cell system A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction.Do molecular signals from the conceptus influence endometrium decidualization in rodents?Vacuolar ATPase regulates zymogen activation in pancreatic acini.The mtDNA nt7778 G/T polymorphism augments formation of lymphocytic foci but does not aggravate cerulein-induced acute pancreatitis in mice

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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.

http://www.wikidata.org/entity/Q40735691

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2000 nî lūn-bûn

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2000年学术文章

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Role of cathepsin B in intrace ...... e onset of acute pancreatitis.

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Role of cathepsin B in intrace ...... e onset of acute pancreatitis.

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Role of cathepsin B in intrace ...... e onset of acute pancreatitis.

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Role of cathepsin B in intrace ...... e onset of acute pancreatitis.

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B Brandt-Nedelev

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C Peters

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H Lippert

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J Deussing

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M Ruthenbuerger

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P2860

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

The structure of the mouse cathepsin B gene and its putative promoter

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins

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10.1172/JCI9411

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6

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106

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12327011

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