about
Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminusRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingThe Drosophila Werner exonuclease participates in an exonuclease-independent response to replication stress.The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links.Human RecQ helicases in DNA repair, recombination, and replication.Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cellsWRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks.Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy.Linkage between Werner syndrome protein and the Mre11 complex via Nbs1.Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle.Regulation of WRN helicase activity in human base excision repair.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
DNA repair and mutagenesis in Werner syndrome.
@en
type
label
DNA repair and mutagenesis in Werner syndrome.
@en
prefLabel
DNA repair and mutagenesis in Werner syndrome.
@en
P2093
P2860
P356
P1476
DNA repair and mutagenesis in Werner syndrome
@en
P2093
P2860
P304
P356
10.1002/EM.1076
P577
2001-01-01T00:00:00Z