The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis.
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Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cellsOverexpression of the tumor autocrine motility factor receptor Gp78, a ubiquitin protein ligase, results in increased ubiquitinylation and decreased secretion of apolipoprotein B100 in HepG2 cellsApolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistanceExpression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditionsFunctional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemiaA novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretionApolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion.Apolipoprotein B-containing lipoprotein assembly in microsomal triglyceride transfer protein-deficient McA-RH7777 cells.Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?Effects of long-term ethanol administration in a rat total enteral nutrition model of alcoholic liver diseaseComplexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins.Identification of protein disulfide isomerase 1 as a key isomerase for disulfide bond formation in apolipoprotein B100.Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance.Lipid metabolism and HCV infectionIntracellular trafficking and secretion of VLDL.Opposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation.Monogenic hypocholesterolaemic lipid disorders and apolipoprotein B metabolism.FoxO1 integrates insulin signaling to VLDL production.Hepatic fatty acid trafficking: multiple forks in the roadApolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly.FoxO1 and hepatic lipid metabolism.The regulation of ApoB metabolism by insulin.Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells.Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B.Lipoprotein assembly and function in an evolutionary perspective.Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.Intracellular assembly of very low density lipoproteins containing apolipoprotein B100 in rat hepatoma McA-RH7777 cells.The conversion of apoB100 low density lipoprotein/high density lipoprotein particles to apoB100 very low density lipoproteins in response to oleic acid occurs in the endoplasmic reticulum and not in the Golgi in McA RH7777 cells.Regulation of hepatic apolipoprotein B-lipoprotein assembly and secretion by the availability of fatty acids. I. Differential response to the delivery of fatty acids via albumin or remnant-like emulsion particles.
P2860
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P2860
The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
The late addition of core lipi ...... nd new triglyceride synthesis.
@en
type
label
The late addition of core lipi ...... nd new triglyceride synthesis.
@en
prefLabel
The late addition of core lipi ...... nd new triglyceride synthesis.
@en
P2093
P2860
P356
P1476
The late addition of core lipi ...... nd new triglyceride synthesis.
@en
P2093
Henry N Ginsberg
Jun-shan Liang Js
Meihui Pan
P2860
P304
P356
10.1074/JBC.M107460200
P407
P577
2001-11-09T00:00:00Z