Stable gene expression from a mammalian artificial chromosome.
about
Efficient assembly of de novo human artificial chromosomes from large genomic loci.A new generation of human artificial chromosomes for functional genomics and gene therapyA highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin geneRapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arraysAssembly and characterization of heterochromatin and euchromatin on human artificial chromosomesA pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challengesHuman artificial chromosome with a conditional centromere for gene delivery and gene expression.Strategies for engineering human chromosomes with therapeutic potential.An artificially constructed de novo human chromosome behaves almost identically to its natural counterpart during metaphase and anaphase in living cellsHuman artificial chromosomes for gene delivery and the development of animal modelsSequence organization and functional annotation of human centromeres.Genetic modification of hematopoietic stem cells with nonviral systems: past progress and future prospects.Inactivation of a human kinetochore by specific targeting of chromatin modifiers.Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere.Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications.Engineering cell-based therapies to interface robustly with host physiology.Using human artificial chromosomes to study centromere assembly and function.A novel human artificial chromosome gene expression system using herpes simplex virus type 1 vectors.Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice.Bacterial transfer of large functional genomic DNA into human cells.Spontaneous transgenesis of human B lymphocytes.Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene.Manipulating transgenes using a chromosome vectorProspects for the use of artificial chromosomes and minichromosome-like episomes in gene therapy.Functional human CFTR produced by a stable minichromosome.Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models.Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies.Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies
P2860
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P2860
Stable gene expression from a mammalian artificial chromosome.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Stable gene expression from a mammalian artificial chromosome.
@en
type
label
Stable gene expression from a mammalian artificial chromosome.
@en
prefLabel
Stable gene expression from a mammalian artificial chromosome.
@en
P2093
P2860
P356
P1433
P1476
Stable gene expression from a mammalian artificial chromosome.
@en
P2093
B R Grimes
D Schindelhauer
N I McGill
T A Ebersole
P2860
P304
P356
10.1093/EMBO-REPORTS/KVE187
P577
2001-09-24T00:00:00Z