Protein phosphatases regulate DNA-dependent protein kinase activity.
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A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombinationA role of DNA-PK for the metabolic gene regulation in response to insulinA PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replicationWhat goes on must come off: phosphatases gate-crash the DNA damage responseIdentification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.DNA-PK autophosphorylation facilitates Artemis endonuclease activityWerner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylationHeat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair fociThe Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage ResponseProteomic characterization of protein phosphatase complexes of the mammalian nucleusAntiadrenergic effects of adenosine A(1) receptor-mediated protein phosphatase 2a activation in the heartValosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells.PP6 regulatory subunit R1 is bidentate anchor for targeting protein phosphatase-6 to DNA-dependent protein kinaseMolecular mechanisms of microcystin toxicity in animal cells.Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins.Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivityPhosphatases in the cellular response to DNA damage.Minichromosome maintenance 2 bound with retroviral Gp70 is localized to cytoplasm and enhances DNA-damage-induced apoptosis.A single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.Regulation of Polo-like kinase 1 by DNA damage in mitosis. Inhibition of mitotic PLK-1 by protein phosphatase 2A.A structural model for regulation of NHEJ by DNA-PKcs autophosphorylationThe DNA-dependent protein kinase: the director at the end.The life and death of DNA-PK.H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues.DNA-PKcs function regulated specifically by protein phosphatase 5Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation.Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors.Taperin (c9orf75), a mutated gene in nonsyndromic deafness, encodes a vertebrate specific, nuclear localized protein phosphatase one alpha (PP1α) docking proteinCellular defects caused by hypomorphic variants of the Bloom syndrome helicase gene BLM.Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors.Implications of tyrosine phosphoproteomics in cervical carcinogenesis.Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.Rapid Diminution in the Level and Activity of DNA-Dependent Protein Kinase in Cancer Cells by a Reactive Nitro-Benzoxadiazole CompoundProtein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair.Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.
P2860
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P2860
Protein phosphatases regulate DNA-dependent protein kinase activity.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Protein phosphatases regulate DNA-dependent protein kinase activity.
@en
type
label
Protein phosphatases regulate DNA-dependent protein kinase activity.
@en
prefLabel
Protein phosphatases regulate DNA-dependent protein kinase activity.
@en
P2093
P356
P1476
Protein phosphatases regulate DNA-dependent protein kinase activity.
@en
P2093
G B Moorhead
S P Lees-Miller
P304
18992-18998
P356
10.1074/JBC.M011703200
P407
P577
2001-03-16T00:00:00Z