Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.
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P1343
ATM activation by ionizing radiation requires BRCA1-associated BAAT1SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stressPPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpointsMultiple roles of ATM in monitoring and maintaining DNA integrityA PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replicationWhat goes on must come off: phosphatases gate-crash the DNA damage responsePathogenesis of ataxia-telangiectasia: the next generation of ATM functionsEmerging Non-Canonical Functions and Regulation by p53: p53 and StemnessPP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpointReactive oxygen species (ROS) homeostasis and redox regulation in cellular signalingThe RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteinsThe Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage ResponseAlpha4 is an essential regulator of PP2A phosphatase activityDynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention.The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia.Modeling the role of p53 pulses in DNA damage- induced cell death decision.Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.Chromatin at the intersection of viral infection and DNA damageATM-dependent ERK signaling via AKT in response to DNA double-strand breaks.HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair.Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications.Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin.Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia.Phosphatases in the cellular response to DNA damage.Minichromosome maintenance 2 bound with retroviral Gp70 is localized to cytoplasm and enhances DNA-damage-induced apoptosis.DNA double-strand break signaling and human disorders.Dephosphorylation of nucleophosmin by PP1β facilitates pRB binding and consequent E2F1-dependent DNA repairProtein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpointDNA damage during reoxygenation elicits a Chk2-dependent checkpoint responsecAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cellsATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.Involvement of novel autophosphorylation sites in ATM activationUse of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures.Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuitDimer monomer transition and dimer re-formation play important role for ATM cellular function during DNA repair.Caveolin-1, cellular senescence and age-related diseases.Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells.PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.Effects of Scorpion venom peptide B5 on hematopoietic recovery in irradiated mice and the primary mechanisms
P2860
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P2860
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 October 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Autophosphorylation of ataxia- ...... ted by protein phosphatase 2A.
@en
Autophosphorylation of ataxia- ...... ted by protein phosphatase 2A.
@nl
type
label
Autophosphorylation of ataxia- ...... ted by protein phosphatase 2A.
@en
Autophosphorylation of ataxia- ...... ted by protein phosphatase 2A.
@nl
prefLabel
Autophosphorylation of ataxia- ...... ted by protein phosphatase 2A.
@en
Autophosphorylation of ataxia- ...... ted by protein phosphatase 2A.
@nl
P2093
P2860
P356
P1433
P1476
Autophosphorylation of ataxia- ...... ted by protein phosphatase 2A.
@en
P2093
Aaron A Goodarzi
David Young
Greg B G Moorhead
Jyoti C Jonnalagadda
Kum Kum Khanna
Pauline Douglas
Ruiqiong Ye
Susan P Lees-Miller
P2860
P304
P356
10.1038/SJ.EMBOJ.7600455
P407
P4510
P577
2004-10-28T00:00:00Z