Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis.
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Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1BSolution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5Cardiac sodium channel Nav1.5 mutations and cardiac arrhythmiaUnraveling the genetics and mechanisms of cardiac arrhythmia.Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a.A common human SCN5A polymorphism modifies expression of an arrhythmia causing mutation.The cardiac sodium channel mutation delQKP 1507-1509 is associated with the expanding phenotypic spectrum of LQT3, conduction disorder, dilated cardiomyopathy, and high incidence of youth sudden deathMutation-specific risk in two genetic forms of type 3 long QT syndrome.Risk stratification in young patients with channelopathies.Congenital and drug-induced long-QT syndrome: an update.Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model.Sodium channel carboxyl-terminal residue regulates fast inactivation.Alternative splicing of the cardiac sodium channel creates multiple variants of mutant T1620K channels.Role of the C-terminal domain in inactivation of brain and cardiac sodium channelsAn EF-hand in the sodium channel couples intracellular calcium to cardiac excitability.Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switchDo defects in ion channel glycosylation set the stage for lethal cardiac arrhythmias?Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndromeA sodium channel pore mutation causing Brugada syndromeComputational biology in the study of cardiac ion channels and cell electrophysiology.Na(+) channel mutation that causes both Brugada and long-QT syndrome phenotypes: a simulation study of mechanism.Differential sialylation modulates voltage-gated Na+ channel gating throughout the developing myocardiumRole of sodium channels in propagation in heart muscle: how subtle genetic alterations result in major arrhythmic disorders.Importance of Knowing the Genotype and the Specific Mutation When Managing Patients with Long QT Syndrome.Mathematical modeling and simulation of ventricular activation sequences: implications for cardiac resynchronization therapy.Mouse Models of SCN5A-Related Cardiac ArrhythmiasInterpreting genetic effects through models of cardiac electromechanics.Computational analysis of the human sinus node action potential: model development and effects of mutations.Long-term flecainide therapy in type 3 long QT syndrome.Quantitative modelling of interaction of propafenone with sodium channels in cardiac cells.Structural effects of an LQT-3 mutation on heart Na+ channel gating.Theoretical investigation of the neuronal Na+ channel SCN1A: abnormal gating and epilepsy.Flecainide sensitivity of a Na channel long QT mutation shows an open-channel blocking mechanism for use-dependent block.Safety and efficacy of flecainide in subjects with Long QT-3 syndrome (DeltaKPQ mutation): a randomized, double-blind, placebo-controlled clinical trial.Sinus Bradycardia in Carriers of the SCN5A-1795insD Mutation: Unraveling the Mechanism through Computer Simulations.Heterogeneity of the properties of INa in epicardial and endocardial cells of rat ventricle.Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure.
P2860
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P2860
Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis.
description
2000 nî lūn-bûn
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2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
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name
Arrhythmogenic mechanism of an ...... nit: A computational analysis.
@en
type
label
Arrhythmogenic mechanism of an ...... nit: A computational analysis.
@en
prefLabel
Arrhythmogenic mechanism of an ...... nit: A computational analysis.
@en
P2093
P356
P1433
P1476
Arrhythmogenic mechanism of an ...... nit: A computational analysis.
@en
P2093
P304
P356
10.1161/01.CIR.102.5.584
P407
P577
2000-08-01T00:00:00Z