Retroviral transfection of Madin-Darby canine kidney cells with human MDR1 results in a major increase in globotriaosylceramide and 10(5)- to 10(6)-fold increased cell sensitivity to verocytotoxin. Role of p-glycoprotein in glycolipid synthesis.
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Mucosal injuries due to ribosome-inactivating stress and the compensatory responses of the intestinal epithelial barrierGlucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling.Sphingolipid transport: rafts and translocators.P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype.The chlamydial inclusion preferentially intercepts basolaterally directed sphingomyelin-containing exocytic vacuoles.Multidrug transporters in prokaryotic and eukaryotic cells: physiological functions and transport mechanisms.Inhibition of glucosylceramide synthase does not reverse drug resistance in cancer cells.The association of Shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effectThe development of aggressive cancer: a possible role for sphingolipids.Shiga-like toxin II impairs hepatobiliary transport of doxorubicin in rats by down-regulation of hepatic P glycoprotein and multidrug resistance-associated protein Mrp2P-glycoprotein antagonists confer synergistic sensitivity to short-chain ceramide in human multidrug-resistant cancer cells.Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway.The fate and function of glycosphingolipid glucosylceramideWhat sugar next? Dimerization of sphingolipid glycosyltransferases.Strategies for overcoming p-glycoprotein-mediated drug resistance in acute myeloblastic leukaemia.Anoikis-resistant MDCK cells carrying susceptibilities to TNF-alpha and verotoxin that are suitable for influenza virus cultivation.Gene therapy with drug resistance genes.New horizon of MDR1 (P-glycoprotein) study.Epithelial and mesenchymal cells in the bovine colonic mucosa differ in their responsiveness to Escherichia coli Shiga toxin 1Glycosphingolipid storage in Fabry mice extends beyond globotriaosylceramide and is affected by ABCB1 depletion.Glycosphingolipid functionsSynthesis of a novel photoactivatable glucosylceramide cross-linker.Differential metabolic responses to pluronic in MDR and non-MDR cells: a novel pathway for chemosensitization of drug resistant cancers.Up-regulation of lactosylceramide synthase in MDR1 overexpressing human liver tumour cells.Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis.The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids.Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.MDR1 P-glycoprotein reduces influx of substrates without affecting membrane potential.Rapid transmembrane diffusion of ceramide and dihydroceramide spin-labelled analogues in the liquid ordered phase.Shiga toxin B-subunit binds to the chaperone BiP and the nucleolar protein B23.Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1).Riboflavin uptake transporter Slc52a2 (RFVT2) is upregulated in the mouse mammary gland during lactation.
P2860
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P2860
Retroviral transfection of Madin-Darby canine kidney cells with human MDR1 results in a major increase in globotriaosylceramide and 10(5)- to 10(6)-fold increased cell sensitivity to verocytotoxin. Role of p-glycoprotein in glycolipid synthesis.
description
2000 nî lūn-bûn
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2000年学术文章
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name
Retroviral transfection of Mad ...... otein in glycolipid synthesis.
@en
type
label
Retroviral transfection of Mad ...... otein in glycolipid synthesis.
@en
prefLabel
Retroviral transfection of Mad ...... otein in glycolipid synthesis.
@en
P2093
P2860
P356
P1476
Retroviral transfection of Mad ...... otein in glycolipid synthesis.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.9.6246
P407
P577
2000-03-01T00:00:00Z