about
Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiationIdentification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progressionNucleophosmin regulates the stability and transcriptional activity of p53Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.The ornithine decarboxylase gene is essential for cell survival during early murine developmentThe Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cellsReciprocal repression between P53 and TCTPJak2 is essential for signaling through a variety of cytokine receptorsExosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null miceG1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target PtprvThe doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammalsNucleophosmin is required for DNA integrity and p19Arf protein stabilityMdmx and Mdm2: brothers in arms?Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional outputDifferential roles of cytokine signaling during T-cell development.Assignment of the human ZNF83 (HPF1) zinc finger gene to chromosome 19q13.3-q13.4.Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivoCop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice.Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.iRegulon: from a gene list to a gene regulatory network using large motif and track collections.Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development.Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.Spontaneous Post-Transplant Disorders in NOD.Cg- Prkdcscid Il2rgtm1Sug/JicTac (NOG) Mice Engrafted with Patient-Derived Metastatic Melanomas.Mdmx as an essential regulator of p53 activity.Targeting Mdmx to treat breast cancers with wild-type p53.p53 attenuates AKT signaling by modulating membrane phospholipid compositionIGF2: the Achilles' heel of p53-deficiency?Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth.Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.MDMX: from bench to bedside.Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity.MDM4 is a key therapeutic target in cutaneous melanoma.Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility.Mdm2-mediated ubiquitylation: p53 and beyond.Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma.MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jean-Christophe Marine
@ast
Jean-Christophe Marine
@en
Jean-Christophe Marine
@es
Jean-Christophe Marine
@sl
type
label
Jean-Christophe Marine
@ast
Jean-Christophe Marine
@en
Jean-Christophe Marine
@es
Jean-Christophe Marine
@sl
prefLabel
Jean-Christophe Marine
@ast
Jean-Christophe Marine
@en
Jean-Christophe Marine
@es
Jean-Christophe Marine
@sl
P1053
K-3292-2016
P106
P21
P31
P3829
P496
0000-0003-2433-9837