p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. - Wikidata - wikimedia - TriplyDB

p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration.

p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration.

http://www.wikidata.org/entity/Q41093716

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HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations Epidermal growth factor suppresses intestinal epithelial cell shedding through a MAPK-dependent pathway The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking NOD-like receptors in intestinal homeostasis and epithelial tissue repair.3,3'-Diindolylmethane (DIM) inhibits the growth and invasion of drug-resistant human cancer cells expressing EGFR mutants Activation of epidermal growth factor receptor is required for NTHi-induced NF-κB-dependent inflammation.Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells Endocytosis and intracellular trafficking of ErbBs.Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate.Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution.TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells.Antiageing Mechanisms of a Standardized Supercritical CO 2 Preparation of Black Jack (Bidens pilosa L.) in Human Fibroblasts and Skin Fragments.Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells.L-arginine uptake by cationic amino acid transporter 2 is essential for colonic epithelial cell restitution.Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition Late endosomal traffic of the epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling Tetrathiomolybdate mediates cisplatin-induced p38 signaling and EGFR degradation and enhances response to cisplatin therapy in gynecologic cancers.Neuregulin-4 is a survival factor for colon epithelial cells both in culture and in vivo Bile acids regulate intestinal cell proliferation by modulating EGFR and FXR signaling.The p38 MAPK stress pathway as a tumor suppressor or more?Interleukin-1β enhances cell migration through AP-1 and NF-κB pathway-dependent FGF2 expression in human corneal endothelial cells.Stress-induced endocytosis and degradation of epidermal growth factor receptor are two independent processes.Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism.PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR.Regulation of prolactin receptor levels and activity in breast cancer Tuning of protein kinase circuitry by p38α is vital for epithelial tissue homeostasis.Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38alpha mitogen-activated protein kinase via Sprouty2 downregulation Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest Degradation of activated protein kinases by ubiquitination.Proteasome inactivation promotes p38 mitogen-activated protein kinase-dependent phosphatidylinositol 3-kinase activation and increases interleukin-8 production in retinal pigment epithelial cells.Sodium transport is modulated by p38 kinase-dependent cross-talk between ENaC and Na,K-ATPase in collecting duct principal cells.Suppression of Nestin reveals a critical role for p38-EGFR pathway in neural progenitor cell proliferation.ErbB receptors and their growth factor ligands in pediatric intestinal inflammation.EGFR signaling pathways are wired differently in normal 184A1L5 human mammary epithelial and MDA-MB-231 breast cancer cells.Regulation of neuronal functions by the E3-ubiquitinligase protein associated with MYC (MYCBP2).Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus.

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p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration.

http://www.wikidata.org/entity/Q41093716

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2006 nî lūn-bûn

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name

p38 kinase regulates epidermal ...... lation and cellular migration.

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p38 kinase regulates epidermal ...... lation and cellular migration.

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p38 kinase regulates epidermal ...... lation and cellular migration.

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D Brent Polk

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Karen L Edelblum

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Mark R Frey

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Rebecca S Dise

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P2860

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

The ErbB signaling network: receptor heterodimerization in development and cancer

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

Rab7: a key to lysosome biogenesis

Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation.

Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis.

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