Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

Item
http://www.wikidata.org/entity/Q41103590
Synthesis of nucleoside phosphate and phosphonate prodrugsCycloSal-2'-ara(ribo)-fluoro-2',3'-dideoxyadenosine monophosphates--an effort to solve the structure-activity relationship of 2'-fluoro-ddAComparison of the antiviral activity of hydrophobic amino acid phosphoramidate monoesters of 2'3'-dideoxyadenosine (DDA) and 3'-azido-3'-deoxythymidine (AZT).Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine.Adenine: an important drug scaffold for the design of antiviral agentsActivation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularineEpigenetic targets in human neoplasms.Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.Medicinal chemistry of fluorinated cyclic and acyclic nucleoside phosphonates.Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells.Structural and energetic properties of the potential HIV-1 reverse transcriptase inhibitors d4A and d4G: a comprehensive theoretical investigation.Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents.Phosphoramidate protides of carbocyclic 2',3'-dideoxy-2',3'-didehydro-7-deazaadenosine with potent activity against HIV and HBV.
P2860

Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

Item
http://www.wikidata.org/entity/Q41103590
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Conversion of 2',3'-dideoxyade ...... y virus and hepatitis B virus.
@en
type
label
Conversion of 2',3'-dideoxyade ...... y virus and hepatitis B virus.
@en
prefLabel
Conversion of 2',3'-dideoxyade ...... y virus and hepatitis B virus.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Conversion of 2',3'-dideoxyade ...... cy virus and hepatitis B virus
@en
P2093
P2860
P304
P31
P356
10.1016/S0014-5793(97)00616-9
P407
P433
P478
P50
P577
P698