Phosphoramidate protides of carbocyclic 2',3'-dideoxy-2',3'-didehydro-7-deazaadenosine with potent activity against HIV and HBV.

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Synthesis of nucleoside phosphate and phosphonate prodrugs

P2860

Q26865400-FD447743-2BEB-427A-B932-7A641B86A45D

P2860

Phosphoramidate protides of carbocyclic 2',3'-dideoxy-2',3'-didehydro-7-deazaadenosine with potent activity against HIV and HBV.

Item

http://www.wikidata.org/entity/Q45208901

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年学术文章

@wuu

2004年学术文章

@zh

2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh-hant

name

Phosphoramidate protides of ca ...... activity against HIV and HBV.

@en

Phosphoramidate protides of ca ...... activity against HIV and HBV.

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type

Item

label

Phosphoramidate protides of ca ...... activity against HIV and HBV.

@en

Phosphoramidate protides of ca ...... activity against HIV and HBV.

@nl

prefLabel

Phosphoramidate protides of ca ...... activity against HIV and HBV.

@en

Phosphoramidate protides of ca ...... activity against HIV and HBV.

@nl

P1476

Phosphoramidate protides of ca ...... activity against HIV and HBV.

@en

P2093

Kristjan S Gudmundsson

http://www.w3.org/2001/XMLSchema#string

Lance C Johnson

http://www.w3.org/2001/XMLSchema#string

Lynn D Condreay

http://www.w3.org/2001/XMLSchema#string

Richard Hazen

http://www.w3.org/2001/XMLSchema#string

Susan M Daluge

http://www.w3.org/2001/XMLSchema#string

Zhicheng Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Anti-HIV compound assessment by two novel high capacity assays

Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR

cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system

The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship.

Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA.

Phosphoramidate protides of 2',3'-dideoxy-3'-fluoroadenosine and related nucleosides with potent activity against HIV and HBV.

Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: toward a rational approach for intracellular delivery of nucleoside 5'-monophosphates.

Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyriboside.

3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.

P304

1929-1937

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P31

scholarly article

P356

10.1081/NCN-200040678

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Chris McGuigan

P577

2004-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15628749

http://www.w3.org/2001/XMLSchema#string

Phosphoramidate protides of carbocyclic 2',3'-dideoxy-2',3'-didehydro-7-deazaadenosine with potent activity against HIV and HBV.

about

P2860

P2860

Phosphoramidate protides of carbocyclic 2',3'-dideoxy-2',3'-didehydro-7-deazaadenosine with potent activity against HIV and HBV.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698