The CDC2-related kinase PITALRE is the catalytic subunit of active multimeric protein complexes.
about
Cyclin-dependent kinase 9-cyclin K functions in the replication stress responseIdentification of multiple cyclin subunits of human P-TEFbPITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo.Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stagesCDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNAMAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexesRequirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcriptionTFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcriptionInterplay between cdk9 and NF-kappaB factors determines the level of HIV-1 gene transcription in astrocytic cellsTAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell linesTranscription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitroP-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase IIE1A blocks hyperphosphorylation of p130 and p107 without affecting the phosphorylation status of the retinoblastoma protein.Human and rodent transcription elongation factor P-TEFb: interactions with human immunodeficiency virus type 1 tat and carboxy-terminal domain substrate.Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells.P-TEFb kinase complex phosphorylates histone H1 to regulate expression of cellular and HIV-1 genes.Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription.Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex.CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.Kinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction.Direct inhibition of CDK9 blocks HIV-1 replication without preventing T-cell activation in primary human peripheral blood lymphocytes.Kaposi's sarcoma-associated herpesvirus K-cyclin interacts with Cdk9 and stimulates Cdk9-mediated phosphorylation of p53 tumor suppressorCyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.HEXIM1, a New Player in the p53 PathwayFunctional evolution of cyclin-dependent kinases.Selective control of gene expression by CDK9 in human cellsA kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction.Identification of a cyclin subunit required for the function of Drosophila P-TEFb.Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cellsThe ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat.The C-terminal domain of pol II and a DRB-sensitive kinase are required for 3' processing of U2 snRNA.Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling.P-TEFb is not an essential elongation factor for the intronless human U2 snRNA and histone H2b genes.Differential regulation of the retinoblastoma family of proteins during cell proliferation and differentiation.Recruitment of P-TEFb (Cdk9-Pch1) to chromatin by the cap-methyl transferase Pcm1 in fission yeast.Phosphorylation site specificity of the CDC2-related kinase PITALRE.
P2860
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P2860
The CDC2-related kinase PITALRE is the catalytic subunit of active multimeric protein complexes.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The CDC2-related kinase PITALR ...... multimeric protein complexes.
@en
type
label
The CDC2-related kinase PITALR ...... multimeric protein complexes.
@en
prefLabel
The CDC2-related kinase PITALR ...... multimeric protein complexes.
@en
P2093
P2860
P356
P1433
P1476
The CDC2-related kinase PITALR ...... multimeric protein complexes.
@en
P2093
P2860
P304
P356
10.1042/BJ3190293
P407
P478
319 ( Pt 1)
P577
1996-10-01T00:00:00Z