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Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay.The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAsIdentification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta.SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elementsSMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeastCap-dependent deadenylation of mRNAA Sm-like protein complex that participates in mRNA degradationAlternative splicing and nonsense-mediated mRNA decay regulate mammalian ribosomal gene expression.Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeastAn interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA processing/export and mRNA stability.The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae.Posttranscriptional control of gene expression in yeast.Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3pMtt1 is a Upf1-like helicase that interacts with the translation termination factors and whose overexpression can modulate termination efficiency.Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathwayA naturally occurring non-coding fusion transcript derived from scorpion venom gland: implication for the regulation of scorpion toxin gene expression.A brome mosaic virus intergenic RNA3 replication signal functions with viral replication protein 1a to dramatically stabilize RNA in vivo.Activity and expression of ADP-glucose pyrophosphorylase during rhizome formation in lotus (Nelumbo nucifera Gaertn.).Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover.Translation repression by GLD-1 protects its mRNA targets from nonsense-mediated mRNA decay in C. elegans.At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation.Post-termination ribosome interactions with the 5'UTR modulate yeast mRNA stabilityIdentifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA.Mutations in VPS16 and MRT1 stabilize mRNAs by activating an inhibitor of the decapping enzymeUpstream open reading frames as regulators of mRNA translation.Nonsense-mediated decay of human HEXA mRNA.Saturation mutagenesis of 5S rRNA in Saccharomyces cerevisiae.T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts.Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay.Characteristics of post-transcriptional gene silencing.smg-7 is required for mRNA surveillance in Caenorhabditis elegans.Roles of the C terminus of Armadillo in Wingless signaling in DrosophilaInhibition of mRNA turnover in yeast by an xrn1 mutation enhances the requirement for eIF4E binding to eIF4G and for proper capping of transcripts by Ceg1pCharacterization of the EYE2 gene required for eyespot assembly in Chlamydomonas reinhardtiiIdentification of putative programmed -1 ribosomal frameshift signals in large DNA databasesThe upf3 protein is a component of the surveillance complex that monitors both translation and mRNA turnover and affects viral propagation.A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells.The role of nuclear cap binding protein Cbc1p of yeast in mRNA termination and degradation.
P2860
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P2860
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Making sense of nonsense in yeast.
@en
type
label
Making sense of nonsense in yeast.
@en
prefLabel
Making sense of nonsense in yeast.
@en
P2093
P1476
Making sense of nonsense in yeast.
@en
P2093
Czaplinski K
Ruiz-Echevarria MJ
P304
P356
10.1016/S0968-0004(96)10055-4
P577
1996-11-01T00:00:00Z