Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs.
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A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteinsNSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathwayCMS: an adapter molecule involved in cytoskeletal rearrangementsBCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cellsSH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreadingAck1 mediates Cdc42-dependent cell migration and signaling to p130CasCAS/Crk coupling serves as a "molecular switch" for induction of cell migration.ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disksCell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments.Calcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling eventsIntroduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinasesTransformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligandIdentification of p130Cas as a mediator of focal adhesion kinase-promoted cell migrationDirect binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas)Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substratesEvidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinasesInvolvement of the tyrosine kinase fer in cell adhesionTyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migrationTyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling.The docking protein HEF1 is an apoptotic mediator at focal adhesion sitesCAS proteins in normal and pathological cell growth controlFibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteinsA novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesionIdentification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membraneStructure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytesA p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signalingCD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhereFyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in T-cell receptor-mediated signallingCytoskeleton-dependent tyrosine phosphorylation of the p130(Cas) family member HEF1 downstream of the G protein-coupled calcitonin receptor. Calcitonin induces the association of HEF1, paxillin, and focal adhesion kinaseCIZ, a zinc finger protein that interacts with p130(cas) and activates the expression of matrix metalloproteinasesProteolysis of the docking protein HEF1 and implications for focal adhesion dynamicsRegulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesionThe PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesionsRegulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesionsDirect association of protein-tyrosine phosphatase PTP-PEST with paxillinCas and NEDD9 Contribute to Tumor Progression through Dynamic Regulation of the Cytoskeleton.Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion
P2860
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P2860
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Integrin-mediated cell adhesio ...... Src homology 2-binding motifs.
@en
type
label
Integrin-mediated cell adhesio ...... Src homology 2-binding motifs.
@en
prefLabel
Integrin-mediated cell adhesio ...... Src homology 2-binding motifs.
@en
P2093
P2860
P356
P1476
Integrin-mediated cell adhesio ...... Src homology 2-binding motifs.
@en
P2093
Hamasaki K
Morimoto C
Tachibana K
P2860
P304
15398-15402
P356
10.1074/JBC.270.25.15398
P407
P577
1995-06-01T00:00:00Z