about
Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growthM-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to NckHepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformationMultifunctional role of Bcl-2 in malignant transformation and tumorigenesis of Cr(VI)-transformed lung cellsNitric oxide-mediated Bcl-2 stabilization potentiates malignant transformation of human lung epithelial cellsInduction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotubesRERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancerRasGRP4 is a novel Ras activator isolated from acute myeloid leukemiaAquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growthCyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformationRegulation of Sos activity by intramolecular interactions.GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signalingCDC42 and FGD1 cause distinct signaling and transforming activities.Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformationMultiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activityIntestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferationOncogenic RIT1 mutations in lung adenocarcinoma.Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosisThe pro-apoptotic Ras effector Nore1 may serve as a Ras-regulated tumor suppressor in the lungLeukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoAXPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoCInvolvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformationNegative control of the Myc protein by the stress-responsive kinase Pak214-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domainCcpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor DbsMultifunctional roles for the PH domain of Dbs in regulating Rho GTPase activationLoop 6 of RhoA confers specificity for effector binding, stress fiber formation, and cellular transformationLck regulates Vav activation of members of the Rho family of GTPasesVav2 is an activator of Cdc42, Rac1, and RhoARibosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation.Oncogenic Ras-transformed human fibroblasts exhibit differential changes in contraction and migration in 3D collagen matrices.G2A is an oncogenic G protein-coupled receptor.The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways.Rig is a novel Ras-related protein and potential neural tumor suppressorBone marrow stromal cell-derived growth inhibitor inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis.Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity.Requirement of phospholipase D1 activity in H-RasV12-induced transformationTC21 and Ras share indistinguishable transforming and differentiating activities.The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation
P2860
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P2860
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Biological assays for Ras transformation.
@en
type
label
Biological assays for Ras transformation.
@en
prefLabel
Biological assays for Ras transformation.
@en
P2093
P1476
Biological assays for Ras transformation.
@en
P2093
P304
P356
10.1016/S0076-6879(95)55042-9
P407
P577
1995-01-01T00:00:00Z