Overexpression of the human lysosomal enzyme alpha-L-iduronidase in Chinese hamster ovary cells.
about
Mouse model of Sanfilippo syndrome type B produced by targeted disruption of the gene encoding alpha-N-acetylglucosaminidaseProduction and characterization of recombinant human CLN2 protein for enzyme-replacement therapy in late infantile neuronal ceroid lipofuscinosisIntrathecal enzyme replacement therapy: successful treatment of brain disease via the cerebrospinal fluidInfusion of alpha-galactosidase A reduces tissue globotriaosylceramide storage in patients with Fabry disease.High-level production of recombinant human lysosomal acid alpha-glucosidase in Chinese hamster ovary cells which targets to heart muscle and corrects glycogen accumulation in fibroblasts from patients with Pompe diseaseSafe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes.Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type INAGLU mutations underlying Sanfilippo syndrome type B.Pharmacokinetic and pharmacodynamic evaluation of elosulfase alfa, an enzyme replacement therapy in patients with Morquio A syndrome.Enzyme replacement therapy for the mucopolysaccharide storage disorders.Successful induction of immune tolerance to enzyme replacement therapy in canine mucopolysaccharidosis IIntrathecal gene therapy corrects CNS pathology in a feline model of mucopolysaccharidosis IBiochemical characterization of fluorescent-labeled recombinant human alpha-L-iduronidase in vitro.Enzyme replacement in a canine model of Hurler syndrome.The first 5 years of clinical experience with laronidase enzyme replacement therapy for mucopolysaccharidosis I.Hematopoietic stem cell transplantation improves the high incidence of neutralizing allo-antibodies observed in Hurler's syndrome after pharmacological enzyme replacement therapy.Immune tolerance improves the efficacy of enzyme replacement therapy in canine mucopolysaccharidosis I.Glycosylation-independent targeting enhances enzyme delivery to lysosomes and decreases storage in mucopolysaccharidosis type VII miceCarbohydrate structures of recombinant human alpha-L-iduronidase secreted by Chinese hamster ovary cells.Aptamer-based endocytosis of a lysosomal enzyme.Proteomics of the lysosome.Insulin-like growth factor II peptide fusion enables uptake and lysosomal delivery of α-N-acetylglucosaminidase to mucopolysaccharidosis type IIIB fibroblasts.Lipoprotein receptor binding, cellular uptake, and lysosomal delivery of fusions between the receptor-associated protein (RAP) and alpha-L-iduronidase or acid alpha-glucosidase.Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives.alpha-L-iduronidase therapy for mucopolysaccharidosis type I.Continuous infusion of enzyme replacement therapy is inferior to weekly infusions in MPS I dogs.In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors.
P2860
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P2860
Overexpression of the human lysosomal enzyme alpha-L-iduronidase in Chinese hamster ovary cells.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Overexpression of the human ly ...... n Chinese hamster ovary cells.
@en
type
label
Overexpression of the human ly ...... n Chinese hamster ovary cells.
@en
prefLabel
Overexpression of the human ly ...... n Chinese hamster ovary cells.
@en
P2093
P356
P1476
Overexpression of the human ly ...... n Chinese hamster ovary cells.
@en
P2093
P304
P356
10.1006/PREP.1994.1035
P577
1994-06-01T00:00:00Z