Systematic exploration of essential yeast gene function with temperature-sensitive mutants.
about
Trait variation in yeast is defined by population historyAn algorithm for chemical genomic profiling that minimizes batch effects: bucket evaluationsIn vitro evolution goes deepSynthetic biology: lessons from engineering yeast MAPK signalling pathwaysEssential genetic interactors of SIR2 required for spatial sequestration and asymmetrical inheritance of protein aggregatesViral Replication Protein Inhibits Cellular Cofilin Actin Depolymerization Factor to Regulate the Actin Network and Promote Viral Replicase AssemblyPolarized Exocytosis Induces Compensatory Endocytosis by Sec4p-Regulated Cortical Actin PolymerizationAltered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus.Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stressMultiple roles for the Ess1 prolyl isomerase in the RNA polymerase II transcription cycle.Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich formins in Saccharomyces cerevisiae.SEACing the GAP that nEGOCiates TORC1 activation: evolutionary conservation of Rag GTPase regulation.Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin.Bub1 kinase and Sgo1 modulate pericentric chromatin in response to altered microtubule dynamicsSgo1 regulates both condensin and Ipl1/Aurora B to promote chromosome biorientation.Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress.An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic developmentBck2 acts through the MADS box protein Mcm1 to activate cell-cycle-regulated genes in budding yeastReverse PCA, a systematic approach for identifying genes important for the physical interaction between protein pairsThe role of Ctk1 kinase in termination of small non-coding RNAsBudding yeast for budding geneticists: a primer on the Saccharomyces cerevisiae model systemThe yeast deletion collection: a decade of functional genomicsIdentifying pathogenicity of human variants via paralog-based yeast complementation.eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequencesHealing for destruction: tRNA intron degradation in yeast is a two-step cytoplasmic process catalyzed by tRNA ligase Rlg1 and 5'-to-3' exonuclease Xrn1.An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential GenesNeighborhood properties are important determinants of temperature sensitive mutations.Requirement of the spindle pole body for targeting and/or tethering proteins to the inner nuclear membrane.Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport.Synthetic lethality of cohesins with PARPs and replication fork mediators.The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast.Linking yeast Gcn5p catalytic function and gene regulation using a quantitative, graded dominant mutant approachInteraction landscape of membrane-protein complexes in Saccharomyces cerevisiae.Conserved regulators of nucleolar size revealed by global phenotypic analyses.Autophagy competes for a common phosphatidylethanolamine pool with major cellular PE-consuming pathways in Saccharomyces cerevisiae.Evaluation of the lower protein limit in the budding yeast Saccharomyces cerevisiae using TIPI-gTOW.The expanding functions of cellular helicases: the tombusvirus RNA replication enhancer co-opts the plant eIF4AIII-like AtRH2 and the DDX5-like AtRH5 DEAD-box RNA helicases to promote viral asymmetric RNA replication.Global analysis of fungal morphology exposes mechanisms of host cell escape.Stress granule-defective mutants deregulate stress responsive transcripts.Genome-Wide Localization Study of Yeast Pex11 Identifies Peroxisome-Mitochondria Interactions through the ERMES Complex.
P2860
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P2860
Systematic exploration of essential yeast gene function with temperature-sensitive mutants.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Systematic exploration of esse ...... temperature-sensitive mutants.
@en
type
label
Systematic exploration of esse ...... temperature-sensitive mutants.
@en
prefLabel
Systematic exploration of esse ...... temperature-sensitive mutants.
@en
P2093
P2860
P50
P356
P1433
P1476
Systematic exploration of esse ...... temperature-sensitive mutants.
@en
P2093
Benjamin Vandersluis
Brenda Andrews
Chad L Myers
Charles Boone
Chris Bulawa
Franco J Vizeacoumar
Frederick S Vizeacoumar
Guri Giaever
James A Fleming
P2860
P2888
P304
P356
10.1038/NBT.1832
P50
P577
2011-03-27T00:00:00Z
P5875
P6179
1032553714