Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres.
about
The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosisMolecular recognition in complexes of TRF proteins with telomeric DNATRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.Telomeres shorten in response to oxidative stress in mouse skeletal muscle fibersCrosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation.Functional characterization of the TERRA transcriptome at damaged telomeres.Cell cycle regulated phosphorylation of the telomere-associated protein TIN2CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase.Chromatin structure in telomere dynamicsPosttranslational control of telomere maintenance and the telomere damage response.Detecting the polymorphism of TERF1 gene by an improved PCR-RFLP method.Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1.Methylated TRF2 associates with the nuclear matrix and serves as a potential biomarker for cellular senescence.Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation.Cockayne Syndrome group B protein interacts with TRF2 and regulates telomere length and stabilityATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance.TRF1 phosphorylation on T271 modulates telomerase-dependent telomere length maintenance as well as the formation of ALT-associated PML bodies.Modulation of telomere protection by the PI3K/AKT pathway.Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity.ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice.
P2860
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P2860
Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Cyclin B-dependent kinase 1 re ...... esolution of sister telomeres.
@en
type
label
Cyclin B-dependent kinase 1 re ...... esolution of sister telomeres.
@en
prefLabel
Cyclin B-dependent kinase 1 re ...... esolution of sister telomeres.
@en
P2860
P356
P1476
Cyclin B-dependent kinase 1 re ...... resolution of sister telomeres
@en
P2093
Megan McKerlie
P2860
P2888
P356
10.1038/NCOMMS1372
P407
P50
P577
2011-06-28T00:00:00Z