Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production.
about
Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switchingB cell receptor editing in tolerance and autoimmunityThe astonishing diversity of Ig classes and B cell repertoires in teleost fishCannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoidsConserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells.Identification of a B cell signature associated with renal transplant tolerance in humans.Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndromeExpansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.A major deletion in the Vκ-Jκ intervening region results in hyperelevated transcription of proximal Vκ genes and a severely restricted repertoire.miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.The Igκ gene enhancers, E3' and Ed, are essential for triggering transcriptionNegative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escapeB cells and autoimmunity.Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing.A new hypersensitive site, HS10, and the enhancers, E3' and Ed, differentially regulate Igκ gene expressionBiased Immunoglobulin Light Chain Gene Usage in the Shark.Vκ gene repertoire and locus contraction are specified by critical DNase I hypersensitive sites within the Vκ-Jκ intervening region.Loss of an Igκ gene enhancer in mature B cells results in rapid gene silencing and partial reversible dedifferentiation.Assembly and Expression of Shark Ig Genes.RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetesNF-kappaB activity marks cells engaged in receptor editing.Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci.Allelic exclusion of immunoglobulin genes: models and mechanisms.Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes.Aberrant B cell selection and activation in systemic lupus erythematosus.Mechanisms of central tolerance for B cells.Respiratory syncytial virus vaccine development
P2860
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P2860
Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Rearrangement of mouse immunog ...... and lambda B cell production.
@en
type
label
Rearrangement of mouse immunog ...... and lambda B cell production.
@en
prefLabel
Rearrangement of mouse immunog ...... and lambda B cell production.
@en
P2093
P2860
P1433
P1476
Rearrangement of mouse immunog ...... and lambda B cell production.
@en
P2093
Bao Hoa Duong
David Nemazee
Djemel Aït-Azzouzene
José Luis Vela
Takayuki Ota
P2860
P304
P356
10.1016/J.IMMUNI.2007.12.011
P407
P577
2008-02-07T00:00:00Z