Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. - Wikidata - wikimedia - TriplyDB

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

http://www.wikidata.org/entity/Q41926372

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Cancer genome landscapes Fundamentals of cancer metabolism ROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic Strategies Cancer Metabolism: A Modeling Perspective Myeloid malignancies: mutations, models and management Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.2-Hydoxyglutarate: D/Riving Pathology in gLiomaS Mutations in CIC and FUBP1 contribute to human oligodendroglioma Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra Management of lower-risk myelodysplastic syndromes without del5q: current approach and future trends.Advanced magnetic resonance imaging of the physical processes in human glioblastoma.Non-invasive metabolic imaging of brain tumours in the era of precision medicine.Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling Molecular Testing of Brain Tumor.Metabolomic analysis and visualization engine for LC-MS data.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia Regulation of the pentose phosphate pathway in cancer Metabolic regulation of stem cell function.Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia.Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress.Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.Oncometabolites: linking altered metabolism with cancer.O-GlcNAc signaling in cancer metabolism and epigenetics CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.Gene mutations and molecularly targeted therapies in acute myeloid leukemia.Emerging role of linker histone variant H1x as a biomarker with prognostic value in astrocytic gliomas. A multivariate analysis including trimethylation of H3K9 and H4K20.Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development.Mutant IDH is sufficient to initiate enchondromatosis in mice.Elevated citrate in pediatric astrocytomas with malignant progression.Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2 Emerging insights into the molecular and cellular basis of glioblastoma.IDH1/2 Mutants Inhibit TET-Promoted Oxidation of RNA 5mC to 5hmC.TET proteins and 5-methylcytosine oxidation in hematological cancers Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells Methylation associated genes contribute to the favorable prognosis of gliomas with isocitrate dehydrogenase 1 mutation.

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

http://www.wikidata.org/entity/Q41926372

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

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type

label

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

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prefLabel

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

@en

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

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P2093

Bryson D Bennett

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Craig B Thompson

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David W White

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Edward M Driggers

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Hyun Gyung Jang

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Joshua D Rabinowitz

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Katharine E Yen

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Kevin M Marks

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Lenny Dang

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Linda M Liau

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P2860

Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria.

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966

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scholarly article

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10.1038/NATURE09132

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7300

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465

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Lewis C. Cantley

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Robert M. Prins

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2010-06-01T00:00:00Z

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1045149705

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3766976

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