The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization
about
Life history and developmental processes in the basidiomycete Coprinus cinereusDominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments.Expression of brain-specific angiogenesis inhibitor 2 (BAI2) in normal and ischemic brain: involvement of BAI2 in the ischemia-induced brain angiogenesisTargeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearanceInvited review: GPCR structural characterization: Using fragments as building blocks to determine a complete structure.Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast: identification of second-site mutations that restore function to a coupling-deficient mutant M3 receptor.Structure of segments of a G protein-coupled receptor: CD and NMR analysis of the Saccharomyces cerevisiae tridecapeptide pheromone receptor.Identification of a polar region in transmembrane domain 6 that regulates the function of the G protein-coupled alpha-factor receptorSignalling in the yeasts: an informational cascade with links to the filamentous fungi.Comparison of class A and D G protein-coupled receptors: common features in structure and activation.Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.Extragenic suppressors of loss-of-function mutations in the aspergillus FlbA regulator of G-protein signaling domain protein.The cytoplasmic end of transmembrane domain 3 regulates the activity of the Saccharomyces cerevisiae G-protein-coupled alpha-factor receptorChanges in conformation at the cytoplasmic ends of the fifth and sixth transmembrane helices of a yeast G protein-coupled receptor in response to ligand binding.Comparative Analysis of Transmembrane Regulators of the Filamentous Growth Mitogen-Activated Protein Kinase Pathway Uncovers Functional and Regulatory DifferencesAgonist-specific conformational changes in the yeast alpha-factor pheromone receptor.Carboxyl-terminal domains determine internalization and recycling characteristics of bombesin receptor chimeras.Accessibility of cysteine residues substituted into the cytoplasmic regions of the alpha-factor receptor identifies the intracellular residues that are available for G protein interaction.Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions.Chemical gradients and chemotropism in yeast.Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor.Fungal mating pheromones: choreographing the dating gameThe regulation of filamentous growth in yeast.Influence of second and third cytoplasmic loops on binding, internalization, and coupling of chimeric bombesin/m3 muscarinic receptors.Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors.The C terminus of the Saccharomyces cerevisiae alpha-factor receptor contributes to the formation of preactivation complexes with its cognate G protein.Defining pheromone-receptor signaling in Candida albicans and related asexual Candida species.Analysis of random PCR-originated mutants of the yeast Ste2 and Ste3 receptors.A Candida albicans-specific region of the alpha-pheromone receptor plays a selective role in the white cell pheromone response.Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that "silence" a constitutively active mutant M3 receptor and greatly impair receptor/G protein coupling.Interacting residues in an activated state of a G protein-coupled receptor.Variable Dependence of Signaling Output on Agonist Occupancy of Ste2p, a G Protein-coupled Receptor in Yeast.
P2860
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P2860
The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The third cytoplasmic loop of ...... , and receptor internalization
@en
type
label
The third cytoplasmic loop of ...... , and receptor internalization
@en
prefLabel
The third cytoplasmic loop of ...... , and receptor internalization
@en
P2860
P356
P1476
The third cytoplasmic loop of ...... , and receptor internalization
@en
P2093
C J Stefan
K J Blumer
P2860
P304
P356
10.1128/MCB.14.5.3339
P407
P577
1994-05-01T00:00:00Z