Common and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemias.
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Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunitiesStress and Non-Stress Roles of Inflammatory Signals during HSC Emergence and MaintenanceTargeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia.Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaA systems biology approach reveals common metastatic pathways in osteosarcoma.NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival.Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia.A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.High expression of LMO2 predicts a favorable outcome in adult patients with BCR/ABL negative B-cell acute lymphoblastic leukemia.Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletionsMyeloid differentiation and the leukemia-initiating cellPML-RARα co-operates with Sox4 in acute myeloid leukemia development in miceTargeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection.HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.Recent advances in acute myeloid leukemia stem cell biologyThe role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe?Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemiaEmerging therapeutic aspects in oncology.Emerging roles of transit-amplifying cells in tissue regeneration and cancer.Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafishSelectively targeting Mcl-1 for the treatment of acute myelogenous leukemia and solid tumors.Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling.Trib2 expression in granulocyte-monocyte progenitors drives a highly drug resistant acute myeloid leukaemia linked to elevated Bcl2.
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Common and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemias.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
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2011年學術文章
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name
Common and overlapping oncogen ...... on of acute myeloid leukemias.
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Common and overlapping oncogen ...... on of acute myeloid leukemias.
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type
label
Common and overlapping oncogen ...... on of acute myeloid leukemias.
@en
Common and overlapping oncogen ...... on of acute myeloid leukemias.
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prefLabel
Common and overlapping oncogen ...... on of acute myeloid leukemias.
@en
Common and overlapping oncogen ...... on of acute myeloid leukemias.
@nl
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P2860
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Common and overlapping oncogen ...... on of acute myeloid leukemias.
@en
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Axel Benner
Benjamin H Lee
Brian J P Huntly
Brynn T Kvinlaug
Christopher Sears
D Gary Gilliland
Donna Foster
Inusha De Silva
Lars Bullinger
Mukundhan Ramaswami
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P304
P356
10.1158/0008-5472.CAN-11-0176
P407
P577
2011-04-19T00:00:00Z