Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts.
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The heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytesGRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulationGenistein inhibits cell growth by modulating various mitogen-activated protein kinases and AKT in cervical cancer cellsMolecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptorscAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factorMechanisms through which Sos-1 coordinates the activation of Ras and Rac.Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors.Regulation of the adapter molecule Grb2 by the Fc epsilon R1 in the mast cell line RBL2H3.The GRB2/Sem-5 adaptor protein.Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice.FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase.Mapping of the C5a receptor signal transduction network in human neutrophils.A minor tyrosine phosphorylation site located within the CAIN domain plays a critical role in regulating tissue-specific transformation by erbB kinaseAbsolute Quantification of Endogenous Ras Isoform AbundanceAntigen-induced B lymphocyte activation involves the p21ras and ras.GAP signaling pathway.Arachidonic acid mediates angiotensin II effects on p21ras in renal proximal tubular cells via the tyrosine kinase-Shc-Grb2-Sos pathway.Repression of platelet-derived growth factor beta-receptor expression by mitogenic growth factors and transforming oncogenes in murine 3T3 fibroblasts.Feedback activation of neurofibromin terminates growth factor-induced Ras activation.Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to RasActivation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.ras effector loop mutations that dissociate p120GAP and neurofibromin interactions.Functional role of GTPase-activating protein in cell transformation by pp60v-srcRegulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factorOverexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice.Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells.Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression.Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration.Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen.Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways.The mechanism of heat shock activation of ERK mitogen-activated protein kinases in the interleukin 3-dependent ProB cell line BaF3.Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites.Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.The insulin-dependent biosynthesis of GLUT1 and GLUT3 glucose transporters in L6 muscle cells is mediated by distinct pathways. Roles of p21ras and pp70 S6 kinase.Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras.p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes.Activation of the Ras/mitogen-activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3-L1 adipocytes.Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells.Oncogenic HRAS mutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome.Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor
P2860
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P2860
Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Epidermal growth factor regula ...... ides on p21ras in fibroblasts.
@en
Epidermal growth factor regula ...... ides on p21ras in fibroblasts.
@nl
type
label
Epidermal growth factor regula ...... ides on p21ras in fibroblasts.
@en
Epidermal growth factor regula ...... ides on p21ras in fibroblasts.
@nl
prefLabel
Epidermal growth factor regula ...... ides on p21ras in fibroblasts.
@en
Epidermal growth factor regula ...... ides on p21ras in fibroblasts.
@nl
P2860
P356
P1476
Epidermal growth factor regula ...... ides on p21ras in fibroblasts.
@en
P2093
P2860
P304
P356
10.1128/MCB.13.3.1903
P407
P577
1993-03-01T00:00:00Z