The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib - Wikidata - wikimedia - TriplyDB

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

http://www.wikidata.org/entity/Q42037254

about

Polyamines and cancer: implications for chemotherapy and chemoprevention Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors The NEDD8-activating enzyme inhibitor MLN4924 disrupts nucleotide metabolism and augments the efficacy of cytarabine The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO-dependent mechanism.Current status of the polyamine research field Polyamine catabolism and disease.Recent advances in the development of polyamine analogues as antitumor agents.ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis.Polyamines metabolism and breast cancer: state of the art and perspectives.Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways.LncRNA GAS8-AS1 inhibits cell proliferation through ATG5-mediated autophagy in papillary thyroid cancer.Polyamines and Cancer.Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis.Targeting PIM kinase activity significantly augments the efficacy of cytarabine.

P2860

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P2860

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

http://www.wikidata.org/entity/Q42037254

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

@en

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

@nl

type

label

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

@en

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

@nl

prefLabel

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

@en

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

@nl

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0008-5472.CAN-07-6483

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Cancer Research

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The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib

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P2093

Andrew Goodwin

http://www.w3.org/2001/XMLSchema#string

Dorothy Bush

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Janet A Houghton

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Jennifer S Carew

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Jerold E Rehg

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John L Cleveland

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Laurence J Marton

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Robert A Casero

http://www.w3.org/2001/XMLSchema#string

Steffan T Nawrocki

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Venudhar K Reddy

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P2860

Immunohistochemical staining of human spermidine/spermine N1-acetyltransferase superinduced in response to treatment with antitumor polyamine analogues

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.

Trans-scleral delivery of polyamine analogs for ocular neovascularization.

A phase 2 study of bortezomib in relapsed, refractory myeloma.

Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma.

Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure.

The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts.

Polyamines and cancer: old molecules, new understanding.

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

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4783-4790

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10.1158/0008-5472.CAN-07-6483

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12

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