Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L.
about
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramersThe de novo DNA methyltransferase DNMT3A in development and cancerDNA methylation, its mediators and genome integrityInsight into the cooperative DNA binding of the O⁶-alkylguanine DNA alkyltransferase.Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylationEctopic DNMT3L triggers assembly of a repressive complex for retroviral silencing in somatic cells.Epigenetic regulation in neural crest development.Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs.Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylationGlobal hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression.Manipulating the epigenome for the treatment of urological malignancies.Functions of DNA methyltransferase 3-like in germ cells and beyond.Genomic imprinting--the struggle of the genders at the molecular level.A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferaseSynthetic epigenetics-towards intelligent control of epigenetic states and cell identityEpigenetics and Bone Remodeling.Driver mutations of cancer epigenomes.DNA methylation: a new twist in the tail.Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm.Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.Enzymology of Mammalian DNA Methyltransferases.Heterochromatin and the molecular mechanisms of 'parent-of-origin' effects in animals.DNMT3A in Leukemia.Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation.Epigenetic Toxicity of Trichloroethylene: A Single-Molecule Perspective.The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.Localization of a bacterial group II intron-encoded protein in human cells.DNA methyltransferase 1 mutations and mitochondrial pathology: is mtDNA methylated?Epigenetics Europe conference. Munich, Germany, 8-9 September 2011.DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.The DNMT3A R882H mutant displays altered flanking sequence preferences.Dnmt3b Methylates DNA by a Noncooperative Mechanism, and Its Activity Is Unaffected by Manipulations at the Predicted Dimer Interface.The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexesChromatin-dependent allosteric regulation of DNMT3A activity by MeCP2
P2860
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P2860
Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Oligomerization and binding of ...... calization and role of Dnmt3L.
@en
Oligomerization and binding of ...... calization and role of Dnmt3L.
@nl
type
label
Oligomerization and binding of ...... calization and role of Dnmt3L.
@en
Oligomerization and binding of ...... calization and role of Dnmt3L.
@nl
prefLabel
Oligomerization and binding of ...... calization and role of Dnmt3L.
@en
Oligomerization and binding of ...... calization and role of Dnmt3L.
@nl
P2093
P2860
P356
P1476
Oligomerization and binding of ...... calization and role of Dnmt3L.
@en
P2093
Claus Urbanke
Gytis Jankevicius
Nils Anspach
Renata Z Jurkowska
Sergey Ragozin
Wolfgang Nellen
P2860
P304
24200-24207
P356
10.1074/JBC.M111.254987
P407
P577
2011-05-12T00:00:00Z