A collagen-related peptide regulates phospholipase Cgamma2 via phosphatidylinositol 3-kinase in human platelets.
about
Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in plateletsA novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and functionPlatelet activation by von Willebrand factor requires coordinated signaling through thromboxane A2 and Fc gamma IIA receptorGPVI and integrin alphaIIb beta3 signaling in plateletsInhibition of cytoskeletal assembly by cytochalasin B prevents signaling through tyrosine phosphorylation and secretion triggered by collagen but not by thrombinThe tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosisDiscovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergiesPhosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces.Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function.LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.The roles and mechanisms of PAR4 and P2Y12/phosphatidylinositol 3-kinase pathway in maintaining thrombin-induced platelet aggregationSignaling during platelet adhesion and activationSignaling events underlying thrombus formation.Platelet-neutrophil interactions under thromboinflammatory conditionsPhosphatidylinositol 3,4,5-trisphosphate regulates Ca(2+) entry via btk in platelets and megakaryocytes without increasing phospholipase C activity.Ginsenoside-Rp1 inhibits platelet activation and thrombus formation via impaired glycoprotein VI signalling pathway, tyrosine phosphorylation and MAPK activation.Platelet integrins and immunoreceptors.Synthesis and biological applications of collagen-model triple-helical peptides.The heptapeptide LSARLAF mediates platelet activation through phospholipase Cgamma2 independently of glycoprotein IIb-IIIaThe relative role of PLCbeta and PI3Kgamma in platelet activation.ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways.Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in plateletsNon-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation.Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin.Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin.Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex.Ligand Binding Rapidly Induces Disulfide-dependent Dimerization of Glycoprotein VI on the Platelet Plasma Membrane
P2860
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P2860
A collagen-related peptide regulates phospholipase Cgamma2 via phosphatidylinositol 3-kinase in human platelets.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A collagen-related peptide reg ...... l 3-kinase in human platelets.
@en
A collagen-related peptide reg ...... l 3-kinase in human platelets.
@nl
type
label
A collagen-related peptide reg ...... l 3-kinase in human platelets.
@en
A collagen-related peptide reg ...... l 3-kinase in human platelets.
@nl
prefLabel
A collagen-related peptide reg ...... l 3-kinase in human platelets.
@en
A collagen-related peptide reg ...... l 3-kinase in human platelets.
@nl
P2093
P2860
P1433
P1476
A collagen-related peptide reg ...... l 3-kinase in human platelets.
@en
P2093
B Payrastre
J M Pasquet
M G Tomlinson
M P Gratacap
P2860
P304
P356
10.1042/0264-6021:3420171
P407
P478
342 ( Pt 1)
P577
1999-08-01T00:00:00Z