Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels. - Wikidata - wikimedia - TriplyDB

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels.

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels.

http://www.wikidata.org/entity/Q42247303

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Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.Versatile somatic gene transfer for modeling neurodegenerative diseases.Modeling Alzheimer's disease in transgenic rats Pathology associated with AAV mediated expression of beta amyloid or C100 in adult mouse hippocampus and cerebellum The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5.The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.Animal models in the drug discovery pipeline for Alzheimer's disease Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice.Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.Indomethacin counteracts the effects of chronic social defeat stress on emotional but not recognition memory in mice Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo Gene Therapy Models of Alzheimer's Disease and Other Dementias.Matrine improves cognitive impairment and modulates the balance of Th17/Treg cytokines in a rat model of Aβ1-42-induced Alzheimer's disease Normal cognition in transgenic BRI2-Aβ mice.A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory The rat as an animal model of Alzheimer's disease.Modeling Alzheimer's disease with non-transgenic rat models.Alzheimer's disease: experimental models and reality.Amyloid precursor protein and tau transgenic models of Alzheimer's disease: insights from the past and directions for the future Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice.An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.Short Aβ peptides attenuate Aβ42 toxicity in vivo.Practical considerations for choosing a mouse model of Alzheimer's disease.Electrophysiological Techniques for Studying Synaptic Activity In Vivo.Modeling Alzheimer's disease in progeria mice. An age-related concept Neuro-Immuno-Gene- and Genome-Editing-Therapy for Alzheimer's Disease: Are We There Yet?

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P2860

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels.

http://www.wikidata.org/entity/Q42247303

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Novel rat Alzheimer's disease ...... ease hippocampal Abeta levels.

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Novel rat Alzheimer's disease ...... ease hippocampal Abeta levels.

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Novel rat Alzheimer's disease ...... ease hippocampal Abeta levels.

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Novel rat Alzheimer's disease ...... ease hippocampal Abeta levels.

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Novel rat Alzheimer's disease ...... ease hippocampal Abeta levels.

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Novel rat Alzheimer's disease ...... ease hippocampal Abeta levels.

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Molecular Neurodegeneration

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Novel rat Alzheimer's disease ...... rease hippocampal Abeta levels

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Lisa Smithson

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Matthew J During

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Patricia A Lawlor

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Pritam Das

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Robert W Price

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Ross J Bland

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Vallie Holloway

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P2860

A stop-codon mutation in the BRI gene associated with familial British dementia

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

Using animal models to determine the significance of complement activation in Alzheimer's disease

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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Alzheimer's disease

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