Purification and characterization of Gbetagamma-responsive phosphoinositide 3-kinases from pig platelet cytosol.
about
The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent mannerRoles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gammaExpansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimersRegulation of platelet plug formation by phosphoinositide metabolismPI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosisPhosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cellsMost central nervous system D2 dopamine receptors are coupled to their effectors by GoRas is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gammaThe experiences of a biochemist in the evolving world of G protein-dependent signaling.Biphasic activation of PKBalpha/Akt in platelets. Evidence for stimulation both by phosphatidylinositol 3,4-bisphosphate, produced via a novel pathway, and by phosphatidylinositol 3,4,5-trisphosphate.Regulation of neurite outgrowth by G(i/o) signaling pathways.Aggregation of the human high affinity immunoglobulin G receptor (FcgammaRI) activates both tyrosine kinase and G protein-coupled phosphoinositide 3-kinase isoforms.The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.Regulation of T-cell migration and effector functions: insights from in vivo imaging studies.Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1The p110 gamma PI-3 kinase is required for EphA8-stimulated cell migration.Role of phosphatidylinositol 3-kinase and specific protein kinase B isoforms in the suppression of apoptosis mediated by the Abelson protein-tyrosine kinase.An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.SYK is upstream of phosphoinositide 3-kinase in B cell receptor signaling.Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase.Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in plateletsOdor-stimulated phosphatidylinositol 3-kinase in lobster olfactory receptor cells.Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells.Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells.Involvement of PI3-kinase and its association with c-Src in PTH-stimulated rat enterocytes.Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface.A versatile high-throughput screen for inhibitors of lipid kinase activity: development of an immobilized phospholipid plate assay for phosphoinositide 3-kinase gamma.Gbetagamma stimulates phosphoinositide 3-kinase-gamma by direct interaction with two domains of the catalytic p110 subunit.The p110γ PI‐3 kinase is required for the mechanism by which the EphA8‐induced neurites are modulated by ephrin‐A5 engagement
P2860
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P2860
Purification and characterization of Gbetagamma-responsive phosphoinositide 3-kinases from pig platelet cytosol.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Purification and characterizat ...... ses from pig platelet cytosol.
@en
Purification and characterizat ...... ses from pig platelet cytosol.
@nl
type
label
Purification and characterizat ...... ses from pig platelet cytosol.
@en
Purification and characterizat ...... ses from pig platelet cytosol.
@nl
prefLabel
Purification and characterizat ...... ses from pig platelet cytosol.
@en
Purification and characterizat ...... ses from pig platelet cytosol.
@nl
P2860
P356
P1476
Purification and characterizat ...... ses from pig platelet cytosol.
@en
P2093
P2860
P304
14193-14199
P356
10.1074/JBC.272.22.14193
P407
P577
1997-05-01T00:00:00Z