Intracellular signaling mechanisms mediating ghrelin-stimulated growth hormone release in somatotropes.
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Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin.Ghrelin augments murine T-cell proliferation by activation of the phosphatidylinositol-3-kinase, extracellular signal-regulated kinase and protein kinase C signaling pathwaysAcylated and unacylated ghrelin protect MC3T3-E1 cells against tert-butyl hydroperoxide-induced oxidative injury: pharmacological characterization of ghrelin receptor and possible epigenetic involvement.Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis).Does the pituitary somatotrope play a primary role in regulating GH output in metabolic extremes?Cell biology of the ghrelin receptor.From growth hormone-releasing peptides to ghrelin: discovery of new modulators of GH secretion.Assessment of Serum Concentrations of Ghrelin, Obestatin, Omentin-1, and Apelin in Children with Type 1 Diabetes.Ghrelin: a hormone regulating food intake and energy homeostasis.Ghrelin restoration of function in vitro in somatotropes from male mice lacking the Janus kinase (JAK)-binding site of the leptin receptor.Ghrelin and the central regulation of feeding and energy balance.Heterogeneity of ghrelin/growth hormone secretagogue receptors. Toward the understanding of the molecular identity of novel ghrelin/GHS receptors.A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons.Structure and physiological actions of ghrelinUpregulation of voltage-gated calcium channel cav1.3 in bovine somatotropes treated with ghrelin.Impairment of ghrelin synthesis in Helicobacter pylori-colonized stomach: new clues for the pathogenesis of H. pylori-related gastric inflammationFrom Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation.Potassium Current Is Not Affected by Long-Term Exposure to Ghrelin or GHRP-6 in Somatotropes GC Cells.Ghrelin reduces voltage-gated calcium currents in GH₃ cells via cyclic GMP pathways.Growth hormone secretagogues and growth hormone releasing peptides act as orthosteric super-agonists but not allosteric regulators for activation of the G protein Galpha(o1) by the Ghrelin receptor.Upregulation of voltage-gated Na+ channels by long-term activation of the ghrelin-growth hormone secretagogue receptor in clonal GC somatotropes.The hepatocarcinoma cell line HepG2 does not express a GHS-R1a-type ghrelin receptor.Activation of somatostatin 2 receptors in the brain and the periphery induces opposite changes in circulating ghrelin levels: functional implications.Ghrelin induces growth hormone secretion via a nitric oxide/cGMP signalling pathway.Endocrine impact of Helicobacter pylori: focus on ghrelin and ghrelin o-acyltransferaseGhrelin and obestatin modulate growth hormone-releasing hormone release and synaptic inputs onto growth hormone-releasing hormone neurons.Ghrelin is suppressed by glucagon and does not mediate glucagon-related growth hormone release.In vitro and in vivo effects of ghrelin on luteinizing hormone and growth hormone release in goldfish.Subpopulations of somatotropes with differing intracellular calcium concentration responses to secretagogues.Differential involvement of protein kinase C and protein kinase A in ghrelin-induced growth hormone and gonadotrophin release from goldfish (Carassius auratus) pituitary cells.Ghrelin stimulates corticotropin-releasing factor and vasopressin gene expression in rat hypothalamic 4B cells.
P2860
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P2860
Intracellular signaling mechanisms mediating ghrelin-stimulated growth hormone release in somatotropes.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Intracellular signaling mechan ...... rmone release in somatotropes.
@en
Intracellular signaling mechan ...... rmone release in somatotropes.
@nl
type
label
Intracellular signaling mechan ...... rmone release in somatotropes.
@en
Intracellular signaling mechan ...... rmone release in somatotropes.
@nl
prefLabel
Intracellular signaling mechan ...... rmone release in somatotropes.
@en
Intracellular signaling mechan ...... rmone release in somatotropes.
@nl
P2093
P50
P356
P1433
P1476
Intracellular signaling mechan ...... ormone release in somatotropes
@en
P2093
Ernesto Ruiz-Guerrero
Felipe F Casanueva
Francisca Rodríguez-Pacheco
Socorro García-Navarro
P304
P356
10.1210/EN.2003-0723
P407
P577
2003-08-28T00:00:00Z