Transgenic approaches to define the functional role of dual site phospholamban phosphorylation.
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Modulation of cardiac contractility by the phospholamban/SERCA2a regulatomeLong term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathyPhosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice.Phospholamban and cardiac contractility.Long-term obesity promotes alterations in diastolic function induced by reduction of phospholamban phosphorylation at serine-16 without affecting calcium handling.Sarco(endo)plasmic reticulum calcium pumps: recent advances in our understanding of structure/function and biology (review).Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression.SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts.Preserved cardiac function despite marked impairment of cAMP generation.Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart.Cardiac Dysfunction Induced by Obesity Is Not Related to β-Adrenergic System Impairment at the Receptor-Signalling Pathway.The importance of the Thr17 residue of phospholamban as a phosphorylation site under physiological and pathological conditions.Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicingIon channels, transporters, and pumps as targets for heart failure therapyTSH inhibits SERCA2a and the PKA/PLN pathway in rat cardiomyocytes.Akt increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban at Thr17.The role of CaMKII regulation of phospholamban activity in heart disease.Ryanodine receptor studies using genetically engineered mice.Quantitative cardiac phosphoproteomics profiling during ischemia-reperfusion in an immature swine model.Structure of the 1-36 N-terminal fragment of human phospholamban phosphorylated at Ser-16 and Thr-17.Differential regulation of inotropy and lusitropy in overexpressed Gsalpha myocytes through cAMP and Ca2+ channel pathways.Accurate quantitation of phospholamban phosphorylation by immunoblot.Targeted inhibition of Ca2+/calmodulin-dependent protein kinase II in cardiac longitudinal sarcoplasmic reticulum results in decreased phospholamban phosphorylation at threonine 17.Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility.A single site (Ser16) phosphorylation in phospholamban is sufficient in mediating its maximal cardiac responses to beta -agonists.Identification of a protein phosphatase-1/phospholamban complex that is regulated by cAMP-dependent phosphorylation.Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy.Sarcolipin, the shorter homologue of phospholamban, forms oligomeric structures in detergent micelles and in liposomes.Altered SR protein expression associated with contractile dysfunction in diabetic rat hearts.Defective intracellular Ca(2+) signaling contributes to cardiomyopathy in Type 1 diabetic rats.Role of dual-site phospholamban phosphorylation in the stunned heart: insights from phospholamban site-specific mutants.Tandem phosphorylation of Ser-911 and Thr-912 at the C terminus of yeast plasma membrane H+-ATPase leads to glucose-dependent activation.
P2860
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P2860
Transgenic approaches to define the functional role of dual site phospholamban phosphorylation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Transgenic approaches to defin ...... phospholamban phosphorylation.
@en
Transgenic approaches to defin ...... phospholamban phosphorylation.
@nl
type
label
Transgenic approaches to defin ...... phospholamban phosphorylation.
@en
Transgenic approaches to defin ...... phospholamban phosphorylation.
@nl
prefLabel
Transgenic approaches to defin ...... phospholamban phosphorylation.
@en
Transgenic approaches to defin ...... phospholamban phosphorylation.
@nl
P2093
P2860
P356
P1476
Transgenic approaches to defin ...... phospholamban phosphorylation.
@en
P2093
P2860
P304
P356
10.1074/JBC.273.8.4734
P407
P577
1998-02-01T00:00:00Z