Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.
about
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activationProline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulationItk: the rheostat of the T cell response.Simulation of the dynamics of primary immunodeficiencies in CD4+ T-cells.Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiationITK inhibitors in inflammation and immune-mediated disorders.PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.
P2860
Q24671707-DDC48EF4-3E71-418A-847D-38BED046B8A0Q30175387-9209D147-0679-4DC2-A714-BEBA041A402FQ35049534-960E3778-56B3-4A65-91E1-734ADE3372CAQ36356747-EC7F4E40-C75A-4F72-A8AE-2C25BE13B1A6Q36368328-96C5D614-1490-4571-80F0-AFD0941EFE07Q36370893-D0263411-BFE0-4445-AEA3-B447F357F529Q37581866-B5F68909-CF7F-413F-A7D8-763FF642B8BCQ42287222-60486D29-FF13-48C3-927E-1B8A8CAF16E4Q46348775-2E6FA99A-5621-4CC2-9DC9-993E93DD1667Q54408164-D7B69D9F-778F-4868-BA3A-A6ECBACA2FB2
P2860
Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Efficient CD28 signalling lead ...... RC family tyrosine kinase LCK.
@en
Efficient CD28 signalling lead ...... RC family tyrosine kinase LCK.
@nl
type
label
Efficient CD28 signalling lead ...... RC family tyrosine kinase LCK.
@en
Efficient CD28 signalling lead ...... RC family tyrosine kinase LCK.
@nl
prefLabel
Efficient CD28 signalling lead ...... RC family tyrosine kinase LCK.
@en
Efficient CD28 signalling lead ...... RC family tyrosine kinase LCK.
@nl
P2093
P2860
P356
P1433
P1476
Efficient CD28 signalling lead ...... RC family tyrosine kinase LCK.
@en
P2093
J B Imboden
R Lapushin
P2860
P304
P356
10.1042/BJ3301123
P407
P478
330 ( Pt 3)
P577
1998-03-01T00:00:00Z