Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway.
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Non-Canonical Hh Signaling in Cancer-Current Understanding and Future DirectionsA comparative review of canine and human rhabdomyosarcoma with emphasis on classification and pathogenesisMolecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cellsNovel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variantAnalysis of molecular cytogenetic alteration in rhabdomyosarcoma by array comparative genomic hybridizationEmbryonic signaling pathways and rhabdomyosarcoma: contributions to cancer development and opportunities for therapeutic targetingNew therapeutic targets in soft tissue sarcoma.Molecular dynamics simulations of sonic hedgehog-receptor and inhibitor complexes and their applications for potential anticancer agent discoveryGLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axisMitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis.The impact of S6K1 kinase on neuroblastoma cell proliferation is independent of GLI1 signalingSRC family kinase (SFK) inhibition reduces rhabdomyosarcoma cell growth in vitro and in vivo and triggers p38 MAP kinase-mediated differentiationTargeting the Hedgehog signaling pathway in cancer: beyond Smoothened.Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar RhabdomyosarcomaRNA editing of the GLI1 transcription factor modulates the output of Hedgehog signalingC-type natriuretic peptide in combination with sildenafil attenuates proliferation of rhabdomyosarcoma cells.Chromosomal and genetic imbalances in Chinese patients with rhabdomyosarcoma detected by high-resolution array comparative genomic hybridization.Targeting the Hedgehog signaling pathway for cancer therapy.The utility of hedgehog signaling pathway inhibition for cancer.Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.Heparanase-1 and components of the hedgehog signalling pathway are increased in untreated alveolar orbital rhabdomyosarcoma.Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcomaIdentification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1.Calcitriol inhibits hedgehog signaling and induces vitamin d receptor signaling and differentiation in the patched mouse model of embryonal rhabdomyosarcomaDistinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis.Notch, wnt, and hedgehog pathways in rhabdomyosarcoma: from single pathways to an integrated network.Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma.A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma.Ligand-dependent Hedgehog pathway activation in Rhabdomyosarcoma: the oncogenic role of the ligands.Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.Different Response of Mutant and Wildtype Rhabdomyosarcoma Toward SMO and PI3K InhibitorsReproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancerRole of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic Targets
P2860
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P2860
Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Reduction of human embryonal r ...... he hedgehog signaling pathway.
@en
Reduction of human embryonal r ...... he hedgehog signaling pathway.
@nl
type
label
Reduction of human embryonal r ...... he hedgehog signaling pathway.
@en
Reduction of human embryonal r ...... he hedgehog signaling pathway.
@nl
prefLabel
Reduction of human embryonal r ...... he hedgehog signaling pathway.
@en
Reduction of human embryonal r ...... he hedgehog signaling pathway.
@nl
P2093
P2860
P356
P1433
P1476
Reduction of human embryonal r ...... he hedgehog signaling pathway.
@en
P2093
Rune Toftgård
Takashi Shimokawa
Ulrica Tostar
P2860
P304
P356
10.1177/1947601910385449
P577
2010-09-01T00:00:00Z